Serotonin receptor 4 / HTR4 antibody

Principal name

Serotonin receptor 4 / HTR4 antibody

Alternative names for Serotonin receptor 4 / HTR4 antibody

5-hydroxytryptamine receptor 4, 5-HT4, 5-HT-4

SwissProt ID

O70528 (Cavpo), P97288 (Mouse), Q13639 (Human), Q29006 (Pig), Q62758 (Rat), Q9UE23 (Human)

Gene ID

3360 (HTR4), 25324 (Htr4)

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Eq (Equine), GP (Guinea Pig), Hst (Hamster), Mky (Monkey), Prim (Primate), Bear, Chk (Chicken), Rb (Rabbit)

Available hosts

Rabbit, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of Serotonin receptor 4 / HTR4 antibody

Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. The gene which encodes SR-3 maps to human chromosome 11q23.1-q23.2. SR-4 mediates widespread effects in central and peripheral nervous systems. The gene which encodes SR-4 maps to human chromosome 5q31-q33. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.

General readings

Hancock, D.B., et al. Nat. Genet. 42(1):45-52(2010)
Maillet, M., et al. Biochem. J. 387 (PT 2), 463-471 (2005)
Brattelid, T., et al. Naunyn Schmiedebergs Arch. Pharmacol. 369(6):616-628(2004)
Hiroi, T., et al. Biochem. Biophys. Res. Commun. 289(2):337-344(2001)
Bender, E., et al. J. Neurochem. 74(2):478-489(2000)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serotonin receptor 4 / HTR4 antibody

  Rabbit Polyclonal 5HT4 Receptor Antibody  
Immunocytochemistry/Immunofluorescence: ICC staining of 5HT4 receptor in HeLa cells with FITC (green). Nuclei were counterstained with DAPI (blue). Rabbit Purified Hu ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

  Rabbit polyclonal anti-HTR4 antibody  
Western blot analysis of extracts from NIH-3T3 cells, using HTR4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

  Rabbit polyclonal anti-5-HT-4 antibody  
Western blot analysis of extracts from 293 cells, treated with insulin (0.01U/ml, 15mins), using 5-HT-4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

  Anti-5HT4 Rabbit Polyclonal Antibody  
Gel: 8%SDS-PAGE,Lysate: 40 µg,Lane 1-4: Hela cells, 293T cells, A549 cells, Jurkat cells,Primary antibody: HTR4 Antibody at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 minutes Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

  Rabbit Polyclonal Anti-HTR4 Antibody  
WB Suggested Anti-HTR4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:2500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

  Rabbit Polyclonal Anti-HTR4 Antibody (C-Terminus)  
Anti-5HT4 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Chk, Hu, Mky
50 µg / €400.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

  Rabbit Polyclonal Anti-HTR4 Antibody (Cytoplasmic Domain)  
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hst, Hu, Ms, Rt
50 µg / €400.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

  Rabbit Polyclonal Anti-HTR4 Antibody (C-Terminus)  
Anti-5HT4 Receptor antibody IHC of human brain, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bov, Can, Hu, Rb
50 µg / €400.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 (Cytopl. Dom.) antibody

  Rabbit Polyclonal Anti-HTR4 Antibody (Cytoplasmic Domain)  
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

Serotonin receptor 4 / HTR4 antibody

Western blot (WB) analysis of SR-4 antibody (Cat.-No. AP01189PU-N) in extracts from NIH-3T3 cells. Rabbit Aff - Purified Hu, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Serotonin receptor 4 / HTR4 antibody

Western blot analysis of SR-4 Antibody (Cat.-No AP20472PU-N) in extracts from Hela cells at 1/500 dilution. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Serotonin receptor 4 / HTR4 (237-250) antibody

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Por, Prim, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

Serotonin receptor 4 / HTR4 (N-term) antibody

Western blot analysis of HTR4 Antibody (N-term) Cat.-No AP52130PU-N in MDA-MB453 cell line and mouse liver tissue lysates (35ug/lane). This demonstrates the HTR4 antibody detected the HTR4 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Serotonin receptor 4 / HTR4 antibody

Immunofluorescence analysis of HeLa cells, using 5-HT-4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

Serotonin receptor 4 / HTR4 antibody

Immunofluorescence analysis of HeLa cells, using 5-HT-4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

Serotonin receptor 4 / HTR4 antibody

Immunofluorescence analysis of MCF7 cells, using HTR4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

Serotonin receptor 4 / HTR4 antibody

Immunofluorescence analysis of MCF7 cells, using HTR4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

HTR4 - human gene knockout kit via CRISPR

HTR4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HTR4 - human gene knockout kit via CRISPR

HTR4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HTR4 overexpression lysate

HTR4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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