Serotonin receptor 6 (HTR6) antibody

Principal name

Serotonin receptor 6 (HTR6) antibody

Alternative names for Serotonin receptor 6 (HTR6) antibody

5-hydroxytryptamine receptor 6, 5-HT-6

SwissProt ID

P31388 (Rat), P50406 (Human), Q9R1C8 (Mouse)

Gene ID

3362 (HTR6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Chimp (Chimpanzee), Eq (Equine), Hst (Hamster), Mky (Monkey), Rb (Rabbit), Gorilla

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Serotonin receptor 6 (HTR6) antibody

5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission. This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders. The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion. Some antidepressants and antipsychotics are potent 5-HT6 Receptor antagonists, making this gene valuable for the pharmaceutical industry. 5-HT6 may be involved in the pathogenesis of mood disorders, schizophrenia, in Alzheimer's disease. A splice variant that has a 289bp deletion in the transmembrane region IV and the third intracellular loop has been isolated.
5-HT6 Receptor has been reported primarily in striatum of the brain. Expression has also been seen in stomach, spinal cord, and the lymphoid tissues of rats, including peripheral blood lymphocytes, spleen, and thymus. ESTs have been isolated from brain libraries.

5 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serotonin receptor 6 (HTR6) (C-term) antibody

Human, Brain, Cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

Serotonin receptor 6 (HTR6) antibody

Western blot analysis of extracts from A549 cells, using 5-HT-6 antibody. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serotonin receptor 6 (HTR6) (C-term) antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

Serotonin receptor 6 (HTR6) antibody

Serotonin receptor 6 (HTR6) Rabbit Purified Ms, Rt P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

HTR6 overexpression lysate

HTR6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

5 Item(s)

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