SERPINA12 antibody

Principal name

SERPINA12 antibody

Alternative names for SERPINA12 antibody

Serpin A12, Vaspin, OL-64, Visceral adipose tissue-derived serine protease inhibitor, Visceral adipose-specific serpin

SwissProt ID

Q7TMF5 (Mouse), Q8IW75 (Human), Q8R4Z1 (Rat)

Gene ID

145264 (SERPINA12)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP), Paraffin Sections (P)

Background of SERPINA12 antibody

May modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues.Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin, in egg white), hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin) and tumor suppressor genes (maspin). Most inhibitory serpins target chymotrypsin-like serine proteases. These enzymes are defined by the presence of a nucleophilic serine residue in their catalytic site. Some serpins inhibit other classes of protease. A number of such serpins have been shown to target cysteine proteases. These enzymes differ from serine proteases in that they are defined by the presence of a nucleophilic cysteine residue, rather than a serine residue, in their catalytic site. SerpinA12, also known as OL-64, Visceral adipose tissue-derived serine protease inhibitor, Vaspin, Visceral adipose-specific serpin and SERPINA12, is a secreted protein which belongs to the serpin family. SerpinA12 / Vaspin is expressed in visceral adipose tissues. It may modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. SerpinA12 / Vaspin may be the compensatory molecule in the pathogenesis of metabolic syndrome and SerpinA12 / Vaspin recombinant protein or vaspin-mimicking agents such as vaspin analogs, or small molecule agents may be the link to drug discovery and development.

General readings

Klöting N, Berndt J, Kralisch S, Kovacs P, Fasshauer M, Schön MR, Stumvoll M, Blüher M.
Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes.
Biochem Biophys Res Commun. 2006 Jan 6;339(1):430-6. Epub 2005 Nov 15.
PMID: 16298335

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SERPINA12 antibody

TA305856 (0.5ug/ml) staining of Human Adipose lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SERPINA12 antibody

Rat serum (15ug) was resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human Vaspin (1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 1C4 Purified Hu, Rt E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

SERPINA12 antibody

Rat serum (15ug) was resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human Vaspin (1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 1C4 Purified Hu, Rt E, WB
50 µl / €230.00
  Acris Antibodies GmbH

SERPINA12 antibody

SERPINA12 Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

SERPINA12 antibody

SERPINA12 Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

SERPINA12 antibody

SERPINA12 Rabbit Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

SERPINA12 antibody

SERPINA12 Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Acris Antibodies GmbH

SERPINA12 antibody

Western Blot analysis of SERPINA12 expression in transfected 293T cell line (H00145264-T01) by SERPINA12 MaxPab polyclonal antibody.

Lane 1: SERPINA12 transfected lysate(45.54 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

SERPINA12 antibody

Immunoprecipitation of SERPINA12 transfected lysate using anti-SERPINA12 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SERPINA12 MaxPab mouse polyclonal antibody (B01) (H00145264-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

SERPINA12 antibody

Western Blot analysis of SERPINA12 expression in transfected 293T cell line (H00145264-T01) by SERPINA12 MaxPab polyclonal antibody.

Lane 1: SERPINA12 transfected lysate(47.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SERPINA12 antibody

Detection limit for recombinant GST tagged SERPINA12 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 3B3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SERPINA12 antibody

Western blot analysis of rat serum ( 15 ug ) was resolved by SDS - PAGE, transferred to NC membrane and probed with SERPINA12 monoclonal antibody, clone 1C4 ( 1 : 2000 ) ( Cat # MAB1106 ) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 1C4 Hu, Rt E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

SERPINA12 antibody

SERPINA12 polyclonal antibody ( Cat # PAB11581 ) ( 0.5 µg/ml ) staining of human adipose lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SERPINA12 antibody

SERPINA12 Mouse IgG1 1C4 Purified Hu, Rt E, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

SERPINA12 antibody

Western Blot: Anti-SERPINA12 Antibody [NBP1-20972]-(0.5ug/ml) staining of Human Adipose lysate (35ug protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SERPINA12

SERPINA12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SERPINA12

SERPINA12 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

SERPINA12

SERPINA12 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 25 µg / €199.00

Special Price: 25 µg / €139.00

  OriGene Technologies, Inc.

SERPINA12 (21-414, His-tag)

SERPINA12 Human Purified ≥ 90 by SDS-PAGE E. coli
0.5 mg / €1,500.00
  Acris Antibodies GmbH

SERPINA12 (21-414, His-tag)

SERPINA12 Human Purified ≥ 90 by SDS-PAGE E. coli
0.1 mg / €520.00
  Acris Antibodies GmbH

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