Serum amyloid P-component antibody

Principal name

Serum amyloid P-component antibody

Alternative names for Serum amyloid P-component antibody

SAP, APCS, PTX2, 9.5S alpha-1-glycoprotein

SwissProt ID

O19063 (Pig), P02743 (Human), P12246 (Mouse), P23680 (Rat), Q3T004 (Bovin)

Gene ID

325 (APCS), 4325534 (Os01g0209200), 29339 (Apcs), 20219

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Radioimmunoassay (R), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Serum amyloid P-component antibody

APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. This gene has multiple polyadenylation sites.

General readings

Veerhuis,R., Neurobiol. Dis. 19 (1-2), 273-282 (2005)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Serum amyloid P-component antibody

Predicted band size: 25 kDa . Positive control: Kidney tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Serum amyloid P-component antibody

Western blot analysis of extracts of various cell lines , using APCS antibody. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Serum amyloid P-component antibody

Anti-APCS mouse monoclonal antibody (TA505247) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APCS(RC202802). Mouse IgG2a OTI1D6 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Serum amyloid P-component antibody

Anti-APCS mouse monoclonal antibody (TA505248) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APCS(RC202802). Mouse IgG1 OTI1H2 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Serum amyloid P-component antibody

Anti-APCS mouse monoclonal antibody (TA505350) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APCS(RC202802). Mouse IgG1 OTI5A9 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Serum amyloid P-component antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 6E6 Liquid Hu E, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Serum amyloid P-component (C-term) antibody

APCS antibody (C-term) (Cat.-No AP50206PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu E, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Serum amyloid P-component antibody

Serum amyloid P-component Mouse IgG1 5.4A Purified Hu E, R
0.2 mg / €510.00
  Acris Antibodies GmbH

Serum amyloid P-component antibody

APCS polyclonal antibody (A02), Lot # 051011JC01. Western Blot analysis of APCS expression in human ovary cancer. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Serum amyloid P-component antibody

Serum amyloid P-component Mouse IgG2b 4E8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Serum amyloid P-component antibody

Detection limit for recombinant GST tagged APCS is approximately 3ng/ml as a capture antibody. Mouse IgG2a 4F3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Serum amyloid P-component antibody

Immunoblot analysis of human plasma protein. Lane 1 : APCS protein isolated from human plasma. Lane 2 : Human plasma. Mouse IgG1 6E6 Hu E, IP, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Serum amyloid P-component antibody

Human Intestine; Rabbit Anti-APCS Antibody. Catalog Number: ARP41962. Paraffin Embedded Tissue: Human Intestine. Cellular Data: Epithelial cells of intestinal villas. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; APCS antibody - N-terminal region (ARP41962_T100) in Human Intestine cells using Immunohistochemistry Rabbit Aff - Purified Hu, Ms, Por P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

Serum amyloid P-component antibody

Western Blot: Serum Amyloid P Antibody [NBP1-58970] - This Anti-APCS antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Serum amyloid P-component

Serum amyloid P-component Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Serum amyloid P-component

Serum amyloid P-component Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Serum amyloid P-component

Serum amyloid P-component Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Serum amyloid P-component

Serum amyloid P-component Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Serum amyloid P-component

Serum amyloid P-component Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Serum amyloid P-component

Serum amyloid P-component Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

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