SETD2 / HIF1 antibody

Principal name

SETD2 / HIF1 antibody

Alternative names for SETD2 / HIF1 antibody

SET2, HIF-1, HYPB, HIP-1, HIP1, p231HBP, KMT3A, KIAA1732, Histone-lysine N-methyltransferase SETD2, SET domain-containing protein 2, Huntingtin-interacting protein B, Huntingtin yeast partner B, Huntingtin-interacting protein 1, Lysine N-methyltransferase 3A

SwissProt ID

E9Q5F9, Q6ZN53 (Human), Q9BYW2 (Human)

Gene ID

29072 (SETD2), 235626

Available reactivities

Ms (Mouse), Can (Canine), Hu (Human), Rt (Rat), Por (Porcine), Bov (Bovine), Eq (Equine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SETD2 / HIF1 antibody

SET2 is a Histone methyltransferase that methylates 'Lys-36' of Histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. This protein probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. SET2 binds DNA at promoters, and may act as a transcription activator. SET2 binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SET2 belongs to a class of huntingtin interacting proteins characterized by WW motifs.

General readings

Sun XJ, Wei J, Wu XY, Hu M, Wang L, Wang HH, Zhang QH, Chen SJ, Huang QH, Chen Z.Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase.J Biol Chem. 2005 Oct 21;280(42):35261-71. Epub 2005 Aug 22.PMID: 16118227

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SETD2 / HIF1 antibody

TA311412 (0.5 ug/ml) staining of mouse fibroblast lysates transiently expressing different siRNA in second and third lane (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SETD2 / HIF1 antibody

Human HepG2 cellsSETD2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SETD2 / HIF1 antibody

Human recombinant protein fragment corresponding to amino acids 1787-2144 of human SETD2 (NP_054878) produced in E.coli. Mouse IgG1 OTI1C4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SETD2 / HIF1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SETD2 (RC229471, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SETD2. Mouse IgG1 OTI1B4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SETD2 / HIF1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SETD2 (RC229471, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SETD2. Mouse IgG1 OTI3G8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SETD2 / HIF1 antibody

Immunohistochemical staining of paraffin-embedded Human embryonic liver tissue using anti-SETD2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804377) Mouse IgG2a OTI1E1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SETD2 / HIF1 antibody

SETD2 / HIF1 Goat Ms E
0.1 mg / €400.00
  Abnova Taiwan Corp.

SETD2 / HIF1 antibody

Human Placenta; SETD2 antibody - N-terminal region (ARP47617_T100) validated by IHC using Human Placenta lysate at 4.0-8.0.; SETD2 antibody - N-terminal region (ARP47617_T100) in Human Placenta cells using Immunohistochemistry Rabbit Purified Can, Hu, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

SETD2 / HIF1 antibody

SETD2 / HIF1 Rabbit IgG Aff - Purified Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

SETD2 / HIF1 antibody

SETD2 / HIF1 Goat IgG Aff - Purified Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SETD2 / HIF1 antibody

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843] Immunohistochemical staining of human oral mucosa shows moderate nuclear positivity in squamous epithelial cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

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