SF3B1 / SAP155 antibody

Principal name

SF3B1 / SAP155 antibody

Alternative names for SF3B1 / SAP155 antibody

Splicing factor 3B subunit 1, SAP-155, SAP 155, SF3b155, Pre-mRNA-splicing factor SF3b 155 kDa subunit, Spliceosome-associated protein 155

SwissProt ID

O57683 (Xenla), O75533 (Human), P49955 (Yeast), Q10178 (Schpo), Q99NB9 (Mouse)

Gene ID

23451 (SF3B1)

Available reactivities

Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Dros (Drosophila), Hst (Hamster), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SF3B1 / SAP155 antibody

SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron\'s branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron\'s branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

General readings

Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SF3B1 / SAP155 antibody

  Rabbit Polyclonal Anti-SF3B1 Antibody  
WB Suggested Anti-SF3B1 Antibody Titration: 1.25 ug/ml; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SF3B1 / SAP155 antibody

  Rabbit Polyclonal Anti-SF3B1 Antibody  
WB Suggested Anti-SF3B1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Hela cell lysateSF3B1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SF3B1 / SAP155 antibody

  Rabbit Polyclonal Anti-SF3B1 Antibody  
SF3B1 / SAP155 Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SF3B1 / SAP155 antibody

  Rabbit Polyclonal Anti-SF3B1 Antibody  
WB Suggested Anti-SF3B1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate; SF3B1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SF3B1 / SAP155 antibody

Western blot analysis of Sap155 expression in several cells using AM26484AF-N. Mouse IgG2b 1A5 Azide Free Hst, Hu, Ms WB
0.1 mg / €440.00
  Acris Antibodies GmbH

SF3B1 / SAP155 (98-198) antibody

Immunocytochemical detection of Sap155 on 4% PFA fixed HeLa cells with AM26528AF-N. Mouse IgG2b 16 Azide Free Hu, Ms ICC/IF, IP, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SF3B1 / SAP155 (transcript variant 2)

  Recombinant protein of human splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2  
SF3B1 / SAP155 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

SF3B1 overexpression lysate

SF3B1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SF3B1 (mGFP-tagged) - Human splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SF3B1 (mGFP-tagged) - Human splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SF3B1 (Myc-DDK tagged) - Human splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SF3B1 (Myc-DDK tagged) - Human splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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