SFRS2 / SC-35 antibody

Principal name

SFRS2 / SC-35 antibody

Alternative names for SFRS2 / SC-35 antibody

Splicing factor SC35, Splicing component 35 kDa, PR264, Nuclear Speckle Marker, Splicing factor arginine/serine-rich 2

SwissProt ID

P30352 (Chick), Q01130 (Human), Q06A98 (Pig), Q3MHR5 (Bovin), Q62093 (Mouse), Q6PDU1 (Rat)

Gene ID

6427 (SRSF2)

Available reactivities

Amph (Amphibian), Dros (Drosophila), Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunoelectron Microscopy (EM), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of SFRS2 / SC-35 antibody

SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SFRS2 / SC-35 (N-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SFRS2 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SFRS2 / SC-35 (Center) antibody

Western blot analysis of SFRS2 Antibody (Center) (AP18194PU-N) in mouse stomach tissue lysates (35ug/lane). SFRS2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SFRS2 / SC-35 (C-term) antibody

Human HeLa; WB Suggested Anti-SFRS2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Hela Whole Cell. SRSF2 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells.; SFRS2 antibody - C-terminal region (ARP61320_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology


Catalog No.    

SFRS2 293T Cell Transient Overexpression Lysate(Denatured)

SFRS2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

4 Item(s)

per page
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