SGK1 / SGK antibody

Principal name

SGK1 / SGK antibody

Alternative names for SGK1 / SGK antibody

Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1

SwissProt ID

O00141 (Human), Q06226 (Rat), Q9WVC6 (Mouse), Q9XT18 (Rabit)

Gene ID

6446 (SGK1), 20393 (Sgk1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Rb (Rabbit), Ze (Zebrafish), Mky (Monkey), Can (Canine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of SGK1 / SGK antibody

Serum- and glucocorticoid-regulated kinase (SGK) is a serine/threonine protein kinase and a member of the "AGC" subfamily, which includes protein kinases A, G, and C. SGK plays an important role in activating certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. SGK contains a catalytic domain, which is most similar to Akt1 (also known as protein kinase B or PKB). SGK is a downstream target of PI 3-kinase-stimulated growth factor signaling, with 3-phosphoinositidedependent protein kinase 1 (PDK1) capable of phosphorylating the activation- loop of SGK at Threonine-256. The adrenal corticosteroid hormone, Aldosterone, induces the transcription of SGK, which mediates Na + transport by stimulating epithelial sodium channel activity. The SGK promoter contains a glucocorticoid response element and an SP-1 regulatory element, and is a transcriptional target for p53. SGK is also a component of the p38 MAPK-mediated response to hyperosmotic stress. The human SGK gene maps to chromosome 6q23 and encodes the 431-amino acid, 49 kDa SGK protein.

General readings

Maiyar A.C. et al. (1996) J. Biol. Chem.. 271: 12414-12422.Brunet A. et al. (2001) Mol. Cell. Biol. 21:952-65

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SGK1 / SGK antibody

  Rabbit polyclonal SGK (Ab-422) antibody  
Western blot analysis of extracts from Jurkat cells, using SGK (Ab-422) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SGK1 / SGK antibody

  Rabbit polyclonal SGK (Ser422) antibody(Phospho-specific)  
Western blot analysis of extracts from HeLa cells treated with Insulin (0.01U/ml, 15mins), using SGK (phospho-Ser422) antibody (#TA314531, Line 1 and 2)The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SGK1 / SGK antibody

  Rabbit polyclonal anti-SKG-1 antibody  
Affinity Purified anti-SGK-1 antibody was used at a 15 µg/ml to detect nuclear and cytoplasmic signal in a variety of tissues including adrenal, heart, liver, ovary, pancreas, placenta, skin, spleen, testes, thyroid and uterus. Low to moderate levels of background staining were noted. This image shows SGK-1 staining of human pancreas. Tissue was formalin-fixed and paraffin embedded. Personal Communication, Tina Roush, LifeSpanBiosciences, Seattle, WA. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.5 mg / €356.00
  OriGene Technologies, Inc.

SGK1 / SGK (C-term) antibody

  Rabbit Polyclonal SGK1 Antibody  
Western blot analysis of SGK1 in human stomach tissue lysate with SGK1 antibody at (A) 1 and (B) 2 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SGK1 / SGK antibody

  Rabbit Polyclonal SGK Antibody  
Western blot analysis of SGK expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SGK1 / SGK antibody

  Rabbit Polyclonal SGK (Ser422) Antibody (Phospho-specific)  
Western blot analysis of SGK phosphorylation expression in Insulin treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SGK1 / SGK (C-term) antibody

  Goat Anti-SGK Antibody  
TA326326 (2µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Can, Hu, Ms, Rb, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

SGK1 / SGK antibody

  SGK1 Rabbit Polyclonal Antibody  
Western blot analysis of extracts from 293 cells, using Caspase 1 (Phospho-Ser376) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

SGK1 / SGK (1-91) antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2b 3E3 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

SGK1 / SGK antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2b 3C4 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

SGK1 / SGK antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2b 1C4 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

SGK1 / SGK antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 3G8 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

SGK1 / SGK (C-term) antibody

Western blot analysis of SGK
expression in lysate from Rat
kidney (Lane 1) and 3T3 cells
(Lane 2). Rabbit Aff - Purified Hu, Ms, Rt IP, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

SGK1 / SGK antibody

Immunohistochemistry (IHC) analyzes of SGK antibody (Cat.-No.: AP06580PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SGK1 / SGK pSer422 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using SGK (Phospho-Ser422) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

SGK1 / SGK pSer422 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using SGK (Phospho-Ser422) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

SGK1 / SGK pSer78 antibody

Western blot analysis of extracts from 293 cells treated with UV 15', using SGK (Phospho-Ser78) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

SGK1 / SGK pSer78 antibody

Western blot analysis of extracts from 293 cells treated with UV 15', using SGK (Phospho-Ser78) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

SGK1 / SGK antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SGK (Ab-422) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

SGK1 / SGK antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SGK (Ab-422) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

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