SGMS2 antibody

Principal name

SGMS2 antibody

Alternative names for SGMS2 antibody

Sphingomyelin synthase 2, SMS2

SwissProt ID

Q20735 (Caeel), Q4JM44 (Rat), Q8NHU3 (Human), Q9D4B1 (Mouse)

Gene ID

166929 (SGMS2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of SGMS2 antibody

SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).[supplied by OMIM]. Sequence Note: removed 3 bases from the 5\' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2142 BC041369.2 4-2145

General readings

Ding,T., (2008) J. Lipid Res. 49 (2), 376-385

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SGMS2 antibody

WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SGMS2 antibody

WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SGMS2 antibody

Western blot on human brain
lysate (10 µg/lane) using antibody to Sphingomyelin Synthase 2 (0.5 µg/ml). Lane A] 1 µg/ml antibody alone, lane B] antibody plus 3 ug blocking peptide. Blot was developed with Pierce’s Super Sytem West Femto - 1 minute exposure. Rabbit IgG Purified Hu E, WB
0.1 mg / €480.00
  Acris Antibodies GmbH

SGMS2 control peptide

SGMS2 Purified WB
50 µg / €210.00
  Acris Antibodies GmbH

SGMS2 antibody

AP05278PU-N SGMS2 antibody staining of Human kidney section at 2 µg/ml. Anti-rabbit Ig (H+L) HRP conjugate (5 µg/ml) without antigen retrieval. Rabbit IgG Aff - Purified Hu WB
10 Blots / €480.00
  Acris Antibodies GmbH

SGMS2 (C-term) antibody

Western blot analysis of SGMS2 (arrow) using SGMS2 Antibody (C-term) Cat.-No AP53889PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SGMS2 gene. Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SGMS2 (C-term) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SGMS2 Antibody (C-term) Cat.-No AP53890PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SGMS2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SGMS2 antibody

SGMS2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SGMS2 antibody

Western blot analysis of MGC26963 over-expressed 293 cell line, cotransfected with MGC26963 Validated Chimera RNAi ( Cat # H00166929-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MGC26963 monoclonal antibody (M08), clone 7D10 (Cat # H00166929-M08 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG2a 7D10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SGMS2 antibody

Western blot on human brain lysate (10 µg/lane) using SGMS2 polyclonal antibody ( Cat # PAB10380 ) to SGMS2 (0.5 µg/ml).
Lane 1, 1 µg/ml antibody alone.
Lane 2, antibody plus 3 µg blocking peptide. Hu
0.1 mg / €560.00
  Abnova Taiwan Corp.

SGMS2 antibody

Human Heart; WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; SGMS2 antibody - N-terminal region (ARP53077_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SGMS2 antibody

Human 293T; WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: 293T cell lysate; SGMS2 antibody - N-terminal region (ARP53078_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SGMS2 antibody

Western Blot: sphingomyelin synthase 2 Antibody [NBP1-60004] - This Anti-SGMS2 antibody was used in Western Blot of Fetal Heart   tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

SGMS2 antibody

Western Blot: sphingomyelin synthase 2 Antibody [NBP1-60005] - This Anti-SGMS2 antibody was used in Western Blot of 293T     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

SGMS2 antibody

Immunohistochemistry-Paraffin: Sphingomyelin Synthase 2 Antibody [NBP1-92436] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SGMS2

SGMS2 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

SGMS2

SGMS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SGMS2

SGMS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

18 Item(s)

per page
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