SGMS2 antibody

Principal name

SGMS2 antibody

Alternative names for SGMS2 antibody

Sphingomyelin synthase 2, SMS2

SwissProt ID

Q20735 (Caeel), Q4JM44 (Rat), Q8NHU3 (Human), Q9D4B1 (Mouse)

Gene ID

166929 (SGMS2), 74442 (Sgms2), 310849

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of SGMS2 antibody

SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).[supplied by OMIM]. Sequence Note: removed 3 bases from the 5\' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2142 BC041369.2 4-2145

General readings

Ding,T., (2008) J. Lipid Res. 49 (2), 376-385

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SGMS2 antibody

  Rabbit Polyclonal Anti-SGMS2 Antibody  
WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SGMS2 antibody

  Rabbit Polyclonal Anti-SGMS2 Antibody  
WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SGMS2 antibody

Western blot on human brain
lysate (10 µg/lane) using antibody to Sphingomyelin Synthase 2 (0.5 µg/ml). Lane A] 1 µg/ml antibody alone, lane B] antibody plus 3 ug blocking peptide. Blot was developed with Pierce’s Super Sytem West Femto - 1 minute exposure. Rabbit IgG Purified Hu E, WB
0.1 mg / €490.00
  Acris Antibodies GmbH

SGMS2 control peptide

SGMS2 Purified WB
50 µg / €220.00
  Acris Antibodies GmbH

SGMS2 antibody

AP05278PU-N SGMS2 antibody staining of Human kidney section at 2 µg/ml. Anti-rabbit Ig (H+L) HRP conjugate (5 µg/ml) without antigen retrieval. Rabbit IgG Aff - Purified Hu WB
0.1 mg / €490.00
  Acris Antibodies GmbH

SGMS2 (C-term) antibody

Western blot analysis of SGMS2 (arrow) using SGMS2 Antibody (C-term) Cat.-No AP53889PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SGMS2 gene. Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SGMS2 (C-term) antibody

Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SGMS2 Antibody (C-term) Cat.-No AP53890PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SGMS2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SGMS2 - human gene knockout kit via CRISPR

SGMS2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SGMS2 - human gene knockout kit via CRISPR

SGMS2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SGMS2 - human gene knockout kit via CRISPR

SGMS2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SGMS2 - human gene knockout kit via CRISPR

SGMS2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sgms2 - mouse gene knockout kit via CRISPR

Sgms2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Sgms2 - mouse gene knockout kit via CRISPR

Sgms2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sgms2 - mouse gene knockout kit via CRISPR

Sgms2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sgms2 - mouse gene knockout kit via CRISPR

Sgms2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SGMS2 (mGFP-tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SGMS2 (mGFP-tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SGMS2 (mGFP-tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, SGMS2 (mGFP-tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SGMS2 (Myc-DDK tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SGMS2 (Myc-DDK tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, SGMS2 (Myc-DDK tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SGMS2 (Myc-DDK tagged) - Human sphingomyelin synthase 2 (SGMS2), transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Sgms2 (GFP-tagged ORF) - Rat sphingomyelin synthase 2 (Sgms2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Sgms2 (GFP-tagged ORF) - Rat sphingomyelin synthase 2 (Sgms2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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