SGSM1 antibody

Principal name

SGSM1 antibody

Alternative names for SGSM1 antibody

KIAA1941, RUTBC2, Small G protein signaling modulator 1, RUN and TBC1 domain-containing protein 2

Gene ID

129049 (SGSM1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SGSM1 antibody

SGSM1 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular sigl transduction and vesicle transportation. A novel protein family small G protein sigling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neurol sigl transduction and vesicular transportation pathways.

General readings

Bar-Sagi D and Hall A. Ras and Rho GTPases: a family reunion. Cell 2000; 103:227-38.
Colicelli J. Human ras superfamily proteins and related GTPases. Sci. STKE 2004; 250:RE13.
Yang H, Sasaki T, Minoshima S, et al. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics 2007; 90:249-60.
Williams JA, Chen X and Sabbatini ME. Small G proteins as key regulators of pancreatic digestive enzyme secretion. Am. J. Physiol. Endocrinol. Metab. 2009; 296:E405-14.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SGSM1 antibody

Western blot analysis of SGSM1 in human cerebellum tissue lysate with SGSM1 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit Purified Hu, Ms, Rt E, WB
0.1 mg / €345.00
  OriGene Technologies, Inc.

SGSM1 (Center) antibody

Western blot analysis of SGSM1 in human cerebellum tissue lysate with SGSM1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SGSM1 (Center) Control Peptide

Western blot analysis of SGSM1 in human cerebellum tissue lysate with SGSM1 antibody Cat.-No AP55476PU-N at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide Cat.-No. AP55476CP-N.
50 µg / €160.00
  Acris Antibodies GmbH

SGSM1 antibody

Immunohistochemistry-Paraffin: SGSM1 Antibody [NBP1-93564] - Immunohistochemistry-Paraffin: SGSM1 Antibody [NBP1-93564] Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts and moderate in Leydig cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

4 Item(s)

per page
  • LinkedIn