SGSM1 antibody

Principal name

SGSM1 antibody

Alternative names for SGSM1 antibody

KIAA1941, RUTBC2, Small G protein signaling modulator 1, RUN and TBC1 domain-containing protein 2

Gene ID

129049 (SGSM1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SGSM1 antibody

SGSM1 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular sigl transduction and vesicle transportation. A novel protein family small G protein sigling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neurol sigl transduction and vesicular transportation pathways.

General readings

Bar-Sagi D and Hall A. Ras and Rho GTPases: a family reunion. Cell 2000; 103:227-38.
Colicelli J. Human ras superfamily proteins and related GTPases. Sci. STKE 2004; 250:RE13.
Yang H, Sasaki T, Minoshima S, et al. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics 2007; 90:249-60.
Williams JA, Chen X and Sabbatini ME. Small G proteins as key regulators of pancreatic digestive enzyme secretion. Am. J. Physiol. Endocrinol. Metab. 2009; 296:E405-14.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SGSM1 antibody

SGSM1 Rabbit Purified Hu, Ms, Rt E, WB
  OriGene Technologies, Inc.

SGSM1 (Center) antibody

SGSM1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
  OriGene Technologies, Inc.

SGSM1 (Center) Control Peptide

  Acris Antibodies GmbH

SGSM1 antibody

SGSM1 Rabbit IgG Aff - Purified Hu P
  Novus Biologicals Inc.

4 Item(s)

per page
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