SH2B1 / SH2B antibody

Principal name

SH2B1 / SH2B antibody

Alternative names for SH2B1 / SH2B antibody

SH2B adapter protein 1, KIAA1299, SH2 domain-containing protein 1B, Pro-rich PH and SH2 domain-containing signaling mediator

SwissProt ID

Q62985 (Rat), Q91ZM2 (Mouse), Q9NRF2 (Human)

Gene ID

25970 (SH2B1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of SH2B1 / SH2B antibody

Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways mediated by Janus kinase (JAK) and receptor tyrosine kinases, including the receptors of insulin (INS), insulin-like growth factor I (IGF1), nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), platelet-derived growth factor (PDGF) and fibroblast growth factors (FGFs). In growth hormone (GH) signaling, autophosphorylated ('Tyr-813') JAK2 recruits SH2B1, which in turn is phosphorylated by JAK2 on tyrosine residues. These phosphotyrosines form potential binding sites for other signaling proteins. GH also promotes serine/threonine phosphorylation of SH2B1 and these phosphorylated residues may serve to recruit other proteins to the GHR-JAK2-SH2B1 complexes, such as RAC1.

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SH2B1 / SH2B antibody

Western blot analysis of extracts of various cell lines, using SH2B1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

SH2B1 / SH2B antibody

WB Suggested Anti-SH2B1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

SH2B1 / SH2B (C-term) antibody

Western blot analysis using SH2B1 Antibody (C-term) Cat.-No AP53895PU-N in 293 cell line lysates (35ug/lane).This demonstrates the SH2B1 antibody detected the SH2B1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SH2B1 / SH2B antibody

Immunofluorescence of purified MaxPab antibody to SH2B on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

SH2B1 / SH2B antibody

Immunofluorescence of purified MaxPab antibody to SH2B on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SH2B1 / SH2B antibody

Western Blot analysis of SH2B1 expression in transfected 293T cell line (H00025970-T01) by SH2B1 MaxPab polyclonal antibody.

Lane 1: SH2B1 transfected lysate(45.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SH2B1 / SH2B antibody

Western Blot analysis of SH2B1 expression in transfected 293T cell line by SH2B1 monoclonal antibody (M01), clone 2B9.

Lane 1: SH2B1 transfected lysate(52.917 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 2B9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SH2B1 / SH2B antibody

SH2B1 / SH2B Goat Hu, Ms, Rt E
0.1 mg / €390.00
  Abnova Taiwan Corp.

SH2B1 / SH2B antibody

Human Liver; Liver; SH2B1 antibody - middle region (ARP55271_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SH2B1 / SH2B antibody

SH2B1 / SH2B Rabbit IgG Aff - Purified Hu, Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SH2B1 / SH2B

SH2B1 / SH2B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SH2B1 / SH2B

SH2B1 / SH2B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

SH2B1 / SH2B

SH2B1 / SH2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SH2B1 / SH2B

SH2B1 / SH2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SH2B1 293T Cell Transient Overexpression Lysate(Denatured)

SH2B1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

15 Item(s)

per page
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