SH2D1A antibody

Principal name

SH2D1A antibody

Alternative names for SH2D1A antibody

DSHP, SAP, SH2 domain-containing protein 1A, SLAM-associated protein, T-cell signal transduction molecule SAP, Duncan disease SH2-protein, Signaling lymphocytic activation molecule-associated protein

SwissProt ID

B2RZ59 (Rat), O60880 (Human), O88890 (Mouse), Q06AA1 (Pig), Q3ZBB1 (Bovin)

Gene ID

4068 (SH2D1A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Bov (Bovine), Mky (Monkey), Eq (Equine), Can (Canine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Paraffin Sections (P)

Background of SH2D1A antibody

This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Romero X, Benitez D, March S, Vilella R, Miralpeix M, Engel P. , Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4). ,Tissue Antigens. 2004 Aug;64(2):132-44. , PMID: 15245368

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SH2D1A antibody

Western blot analysis of thymus cell lysate using SH2D1A antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

SH2D1A antibody

TA302605 staining (0.3µg/ml) of Human Thymus lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SH2D1A antibody

TA302606 (0.2µg/ml) staining of human lymph node lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SH2D1A antibody

WB Suggested Anti-SH2D1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate SH2D1A is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Eq, Hu, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SH2D1A antibody

Host: Rabbit; Target Name: SH2D1A; Sample Tissue: 293T Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SH2D1A antibody

Western blot analysis using SAP antibody on NK-92 cell lysate at 10 µg/ml). Rabbit IgG Purified Hu IP, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

SH2D1A antibody

Western Blot analysis of SH2D1A expression in transfected 293T cell line (H00004068-T01) by SH2D1A MaxPab polyclonal antibody.

Lane 1: SH2D1A transfected lysate(14.08 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

SH2D1A antibody

Western Blot analysis of SH2D1A expression in transfected 293T cell line (H00004068-T02) by SH2D1A MaxPab polyclonal antibody.

Lane 1: SH2D1A transfected lysate(14.08 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

SH2D1A antibody

Western Blot analysis of SH2D1A expression in transfected 293T cell line (H00004068-T01) by SH2D1A MaxPab polyclonal antibody.

Lane 1: SH2D1A transfected lysate(14.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SH2D1A antibody

Western Blot analysis of SH2D1A expression in transfected 293T cell line by SH2D1A monoclonal antibody (M01), clone 1C9.

Lane 1: SH2D1A transfected lysate(14.2 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 1C9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SH2D1A antibody

SH2D1A polyclonal antibody ( Cat # PAB6819 ) staining ( 0.3 µg/ml ) of human thymus lysate ( RIPA buffer, 30 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SH2D1A antibody

SH2D1A polyclonal antibody ( Cat # PAB6907 ) ( 0.2 µg/ml ) staining of human lymph node lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SH2D1A antibody

Western blot analysis using SH2D1A polyclonal antibody ( Cat # PAB10367 ) on NK-92 cell lysate at 10µg/ml). Rabbit Hu IP, WB
50 µg / €400.00
  Abnova Taiwan Corp.

SH2D1A (C-term) antibody

Human Jurkat; WB Suggested Anti-SH2D1A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate. SH2D1A is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; SH2D1A antibody - C-terminal region (ARP60359_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

SH2D1A antibody

Western blot analysis of SH2D1A expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Por, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

SH2D1A antibody

Western blot analysis of SH2D1A expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Por, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

SH2D1A antibody

Western blot analysis of SH2D1A expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Por, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

SH2D1A antibody

Western Blot: SH2D1A / SAP Antibody [NB100-1895] - HEK293 overexpressing SH2D1A (RC204723) and probed (mock transfection in first lane), tested by Origene. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SH2D1A antibody

Western Blot: SH2D1A Antibody [NB100-40783] - NB100-40783 (0.2ug/ml) staining of Human Lymph Node lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SH2D1A antibody

SH2D1A Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

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