SH3BP2 antibody

Principal name

SH3BP2 antibody

Alternative names for SH3BP2 antibody

SH3 domain-binding protein 2, SH3BP-2, 3BP2, 3BP-2

SwissProt ID

P78314 (Human), Q06649 (Mouse)

Gene ID

6452 (SH3BP2)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Chk (Chicken), Rt (Rat), Bov (Bovine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Sheep

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of SH3BP2 antibody

SH3BP2 Src Homology 3 Binding Protein 2 is also known as 3BP-2 and SH3 Binding Protein 2. The Src homology 3 (SH3) region is a small protein domain presented in a very large group of proteins, including cytoskeletal elements and signaling proteins. SH3 domains are believed to serve as modules that mediate protein-protein associations and, along with Src homology 2 (SH2) domains, regulate cytoplasmic signaling. SH3BP2 is composed of an N terminal pleckstrin homology (PH) domain, a ten aa SH3 binding domain, three modular peptide recognition domains, and a C terminal SH2 domain. SH3BP2 function relates to signal transduction and regulation. SH3BP2 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Phosphorylation of SH3BP2 occurs on S427 for activation. SH3BP2 mediates interactions of huntingtin and MLK2 (mixed lineage kinase). Defects in SH3BP2 are the cause of cherubism (CRBM), an autosomal dominant inherited syndrome. It is characterized by excessive bone degradation of the upper and lower jaws, which often begins around three years of age. It is followed by development of fibrous tissue masses, which causes a characteristic facial swelling.

General readings

Idowu,B.D., (2008) Br J Oral Maxillofac Surg 46 (3), 229-230

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SH3BP2 antibody

WB Suggested Anti-SH3BP2 Antibody Titration: 1 ug/ml; Positive Control: 721_B cell lysateSH3BP2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

SH3BP2 antibody

Western blot analysis using anti-3BP2 at 10 µg/ml on recombinant full lenth 3BP2 protein (1), 3BP2 protein minus the PH domain (2), 3BP2 protein minus the PR domain (3) and 3BP2 protein minus the SH2 domain (4). Sheep IgG Purified Ms WB
0.25 mg / €370.00
  Acris Antibodies GmbH

SH3BP2 (Center) antibody

Western blot analysis using SH3BP2 Antibody (Center) Cat.-No AP53901PU-N in Mouse spleen tissue lysates (35ug/lane).This demonstrates the SH3BP2 antibody detected the SH3BP2 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SH3BP2 pSer427 antibody

Figure 1. Western blot analysis is shown using Affinity Purified anti-SH3BP2 pS427 antibody to detect endogenous protein present in unstimulated human whole cell lysates). The band as indicated by the arrowheads is evident in both M059 cells (panel A) and PC-3 cells (panel B). Comparison to a molecular weight marker indicates a band of ~60 kDa corresponding to human SH3BP2 protein. The blot was incubated with a 1:500 dilution of the antibody at room temperature followed by detection using standard techniques. Personal communication Steven Pelech, Kinexus Inc. Rabbit Aff - Purified Hu E
0.1 mg / €450.00
  Acris Antibodies GmbH

SH3BP2 antibody

Western Blot analysis of SH3BP2 expression in transfected 293T cell line (H00006452-T01) by SH3BP2 MaxPab polyclonal antibody.

Lane 1: SH3BP2 transfected lysate(62.20 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

SH3BP2 antibody

Immunofluorescence of monoclonal antibody to SH3BP2 on A-431 cell. [antibody concentration 20 ug/ml] Mouse IgG2a 1E9 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SH3BP2 antibody

SH3BP2 Sheep Purified Ms WB
0.25 mg / €400.00
  Abnova Taiwan Corp.

SH3BP2 pSer427 antibody

Western blot analysis is shown using SH3BP2 (phospho S427) polyclonal antibody ( Cat # PAB10066 ) to detect endogenous protein present in unstimulated human whole cell lysates.
The bandas indicated by the arrowheads is evident in both M059 cells ( panel A ) and PC-3 cells ( panel B ).
Comparison to a molecular weight marker indicatesa band of ~60 kDa corresponding to human SH3BP2 protein.
The blot was incubated with a 1:500 dilutionof the antibody at room temperature followed by detection using standard techniques.
Personal communication Steven Pelech, Kinexus Inc. Rabbit Hu E, IP, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

SH3BP2 antibody

Human Liver; SH3BP2 antibody - middle region (ARP56546_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified Can, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SH3BP2 (transcript variant 1)

SH3BP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SH3BP2 (transcript variant 2)

SH3BP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SH3BP2

SH3BP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SH3BP2

SH3BP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SH3BP2 overexpression lysate

SH3BP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SH3BP2 overexpression lysate

SH3BP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SH3BP2 (mGFP-tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SH3BP2 (mGFP-tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.

Lenti ORF particles, SH3BP2 (mGFP-tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SH3BP2 (mGFP-tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.

Lenti ORF particles, SH3BP2 (mGFP-tagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, SH3BP2 (mGFP-tagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,270.00
  OriGene Technologies, Inc.

Lenti ORF particles, SH3BP2 (mGFP-tagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, SH3BP2 (mGFP-tagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €1,240.00
  OriGene Technologies, Inc.

Lenti ORF particles, SH3BP2 (Myc-DDK tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SH3BP2 (Myc-DDK tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,070.00
  OriGene Technologies, Inc.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn