SH3KBP1 antibody

Principal name

SH3KBP1 antibody

Alternative names for SH3KBP1 antibody

CIN85, HSB-1, CD2BP3, SH3 domain-containing kinase-binding protein 1, Cbl-interacting protein of 85 kDa, Human Src family kinase-binding protein 1, CD2-binding protein 3

SwissProt ID

Q8R548 (Mouse), Q8R550 (Mouse), Q925Q9 (Rat), Q96B97 (Human)

Gene ID

30011 (SH3KBP1), 84357 (Sh3kbp1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit), GP (Guinea Pig)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of SH3KBP1 antibody

SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules, characterized by containing three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases. SH3KBP1 is involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through a association with CBL and endophilins. In the case of EGF receptor turnover, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalization. Once internalized, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation. Alternate splicing results in multiple transcript variants.

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SH3KBP1 antibody

WB Suggested Anti-SH3KBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SH3KBP1 antibody

WB Suggested Anti-Sh3kbp1 Antibody; Titration: 1.0 ug/ml; Positive Control: Rat Thymus Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SH3KBP1 (2-14) antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Can, Chk, Elephant, Hu, Mky, Ms, Op, Platypus, Prim, Rb, Rt, Ze P
50 µg / €470.00
  Acris Antibodies GmbH

SH3KBP1 antibody

SH3KBP1 Mouse Purified Hu E(detection), P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SH3KBP1 antibody

SH3KBP1 Mouse IgG2a 1F11 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SH3KBP1 antibody

Western Blot: SH3KBP1 Antibody [NBP1-85614] Lane 1: Marker [kDa] 229, 112, 83.5, 47.9, 32.3, 26.5, 17.2 | Lane 2: RT-4 | Lane 3: U-251 MG | Lane 4: Human Plasma | Lane 5: Liver | Lane 6: Tonsil Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

SH3KBP1 antibody

Immunohistochemistry-Paraffin: SH3KBP1 Antibody [NBP1-85615] - Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SH3KBP1 (transcript variant 1)

SH3KBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SH3KBP1 (transcript variant 2)

SH3KBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SH3KBP1

SH3KBP1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

SH3KBP1

SH3KBP1 Human
10 µg / €380.00
  Abnova Taiwan Corp.

SH3KBP1

SH3KBP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SH3KBP1

SH3KBP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SH3KBP1 293T Cell Transient Overexpression Lysate(Denatured)

SH3KBP1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

SH3KBP1 overexpression lysate

SH3KBP1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

SH3KBP1 overexpression lysate

SH3KBP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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