SH3PXD2A antibody

Principal name

SH3PXD2A antibody

Alternative names for SH3PXD2A antibody

FISH, KIAA0418, SH3MD1, TKS5, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, Five SH3 domain-containing protein, Adaptor protein TKS5

SwissProt ID

O89032 (Mouse), Q1LYG0 (Danre), Q5TCZ1 (Human)

Gene ID

9644 (SH3PXD2A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Hst (Hamster), Mky (Monkey), Por (Porcine), Rb (Rabbit), Xen (Xenopus), Gorilla

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunoprecipitation (IP)

Background of SH3PXD2A antibody

Tks5 (previously known as Fish), is a large scaffolding protein with one amino-terminal PX domain and five SH3 domains. It is cytoplasmic in normal fibroblasts. In Src-transformed cells, Tks5 localizes to podosomes. The coexpression of Tks5 and constitutively active Src in epithelial cancer cells resulted in the appearance of podosomes/invadopodia. Cells with reduced Tks5 expression are poorly invasive through matrigel. Tks5 is expressed and localized to podosomes/invadopodia in some invasive human cancer cell lines and tumor tissue, particularly breast cancers and melanomas. Thus, Tks5 appears to be required for podosome/invadopodia formation and for invasion of some cancer cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SH3PXD2A (1033-1046) antibody

SH3PXD2A Goat IgG Purified Hu P
50 µg / €345.00
  OriGene Technologies, Inc.

SH3PXD2A (N-term) antibody

SH3PXD2A Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SH3PXD2A antibody

SH3PXD2A Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

SH3PXD2A antibody

SH3PXD2A Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

SH3PXD2A antibody

SH3PXD2A Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

5 Item(s)

per page
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