SH3RF1 / RNF142 antibody

Principal name

SH3RF1 / RNF142 antibody

Alternative names for SH3RF1 / RNF142 antibody

POSH, SH3MD2, KIAA1494, Putative E3 ubiquitin-protein ligase SH3RF1, SH3 domain-containing RING finger protein 1, Plenty of SH3s, SH3 multiple domains protein 2, RING finger protein 142

SwissProt ID

A5D7F8 (Bovin), A5D8S5 (Danre), Q69ZI1 (Mouse), Q6NRD3 (Xenla), Q71F54 (Rat), Q7Z6J0 (Human)

Gene ID

57630 (SH3RF1)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of SH3RF1 / RNF142 antibody

SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SH3RF1 / RNF142 antibody

WB Suggested Anti-SH3RF1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: DU145 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

SH3RF1 / RNF142 antibody

SH3RF1 / RNF142 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SH3RF1 / RNF142 antibody

SH3MD2 monoclonal antibody (M01), clone 3H3 Western Blot analysis of SH3MD2 expression in HeLa ( Cat # L013V1 ). Mouse IgG2a 3H3 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SH3RF1 / RNF142 antibody

SH3RF1 / RNF142 Mouse IgG2a 1F7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SH3RF1 / RNF142 antibody

Human DU145; WB Suggested Anti-SH3RF1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: DU145 cell lysate; SH3RF1 antibody - middle region (ARP43283_P050) in Human DU145 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SH3RF1 / RNF142 antibody

Western Blot: SH3MD2 Antibody [NBP1-54972] - This Anti-SH3RF1 antibody was used in Western Blot of DU145     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SH3RF1 / RNF142

SH3RF1 / RNF142 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SH3RF1 / RNF142

SH3RF1 / RNF142 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SH3RF1 / RNF142

SH3RF1 / RNF142 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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