SHISA3 antibody

Principal name

SHISA3 antibody

Alternative names for SHISA3 antibody

Protein shisa-3 homolog

SwissProt ID

A0PJX4 (Human), Q3UPR0 (Mouse), Q7T0Z7 (Xenla)

Gene ID

152573 (SHISA3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of SHISA3 antibody

SHISA3 Antibody: SHISA3 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT sigling. The Shisa family of single-transmembrane proteins is characterized by an N-termil cysteine-rich domain and a proline-rich C-termil region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF sigling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslatiol maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt sigling and suppressed head formation during gastrulation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SHISA3 antibody

Western blot analysis of SHISA3 in human small intestine Tissue lysate with SHISA3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SHISA3 (C-term) antibody

Formalin fixed, paraffin embedded human kidney tissue stained with SHISA3 Antibody (C-term) Cat.-No AP53910PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SHISA3

SHISA3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

SHISA3 overexpression lysate

SHISA3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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