Alternative names for SHROOM1 antibody
Protein Shroom1, APXL2, KIAA1960, Apical protein 2
Enzyme Immunoassay (E), Western blot / Immunoblot (WB)
Background of SHROOM1 antibody
SHROOM1 Antibody: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmory arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmory arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmory arterial hypertension.