SIGIRR / TIR8 antibody

Principal name

SIGIRR / TIR8 antibody

Alternative names for SIGIRR / TIR8 antibody

UNQ301/PRO342, Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single immunoglobulin domain-containing IL1R-related protein, Toll/interleukin-1 receptor 8

SwissProt ID

Q4V892 (Rat), Q6IA17 (Human), Q9JLZ8 (Mouse)

Gene ID

59307 (SIGIRR), 24058 (Sigirr)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Chk (Chicken), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Rat

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of SIGIRR / TIR8 antibody

SIGIRR is a member of the Toll-like receptor-interleukin 1 receptor superfamily. Members of this family are defined by the presence of an intracellular Toll-IL-1R (TIR) domain. The Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). SIGIRR was originally identified through database analysis and was shown to have only one Ig domain as opposed to the normal three Ig folds seen in the TIR family (3). Similar to ST2, another TIR family member, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor signaling (4,5). However, SIGIRR inhibits TLR-IL-1R signaling by dimerizing with TLR4, TLR5, TLR9, and IL-1R. It also associates with the down-stream TLR signaling proteins IRAK and TRAF6 in an IL-1-dependent fashion (4).

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SIGIRR / TIR8 (C-term) antibody

Western blot analysis of SIGIRR in A549 cell lysate with SIGIRR antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SIGIRR / TIR8 Control Peptide

SIGIRR / TIR8
50 µg / €160.00
  Acris Antibodies GmbH

SIGIRR / TIR8 antibody

Western Blot analysis of SIGIRR expression in transfected 293T cell line (H00059307-T01) by SIGIRR MaxPab polyclonal antibody.

Lane 1: SIGIRR transfected lysate(45.1 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

SIGIRR / TIR8 antibody

Immunoprecipitation of SIGIRR transfected lysate using anti-SIGIRR MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SIGIRR MaxPab mouse polyclonal antibody (B01) (H00059307-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

SIGIRR / TIR8 antibody

Western Blot analysis of SIGIRR expression in transfected 293T cell line (H00059307-T02) by SIGIRR MaxPab polyclonal antibody.

Lane 1: SIGIRR transfected lysate(45.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SIGIRR / TIR8 antibody

SIGIRR monoclonal antibody (M01A), clone 3H8-2G3 Western Blot analysis of SIGIRR expression in HepG2 ( Cat # L019V1 ). Mouse IgM 3H8-2G3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

SIGIRR / TIR8 antibody

Western blot analysis of human SIGIRR in 15 µgs of ( A ) human kidney and ( B ) mouse kidney cell lysate. Using SIGIRR polyclonal antibody ( Cat # PAB0223 ) at 0.5 µg/ml. Rabbit Hu, Ms WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SIGIRR / TIR8 antibody

Western blot analysis of SIGIRR in 40 µgs of A ) HCT-116 and B ) A-549 cell lysate. Using SIGIRR polyclonal antibody ( Cat # PAB0342 ) at 1 : 500 dilution. Rabbit Hu WB
0.2 ml / €400.00
  Abnova Taiwan Corp.

SIGIRR / TIR8 antibody

Immunocytochemistry of Sigirr in A-549 cells with Sigirr polyclonal antibody ( Cat # PAB12930 ) at 10 µg/ml. Rabbit Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

SIGIRR / TIR8 antibody

Human Liver; Liver; SIGIRR antibody - C-terminal region (ARP49664_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SIGIRR / TIR8 antibody

Immunohistochemistry-Paraffin: SIGIRR Antibody [NBP1-59723] Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rt, Ze P, WB
50 µg / €440.00
  Novus Biologicals Inc.

SIGIRR / TIR8 antibody

SIGIRR / TIR8 Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

SIGIRR / TIR8 antibody

Immunohistochemistry-Paraffin: SIGIRR Antibody [NBP1-86940] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SIGIRR / TIR8 (transcript variant 3)

SIGIRR / TIR8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SIGIRR / TIR8 (transcript variant 2)

SIGIRR / TIR8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SIGIRR / TIR8 (transcript variant 1)

SIGIRR / TIR8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SIGIRR / TIR8

SIGIRR / TIR8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SIGIRR / TIR8

SIGIRR / TIR8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

SIGIRR (Human) IP-WB Antibody Pair

SIGIRR (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SIGIRR 293T Cell Transient Overexpression Lysate(Denatured)

SIGIRR 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn