SIGLEC11 antibody

Principal name

SIGLEC11 antibody

Alternative names for SIGLEC11 antibody

SIGLEC-11, UNQ9222/PRO28718, Sialic acid-binding Ig-like lectin 11, Sialic acid-binding lectin 11

SwissProt ID

Q96RL6 (Human)

Gene ID

114132 (SIGLEC11)

Available reactivities

Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of SIGLEC11 antibody

Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily that are mainly expressed in cells of the hematopoietic system. Siglec11 is unlike other siglecs in that it binds specifically to alpha2-8-linked sialic acids and is not found in peripheral blood leukocytes but instead on macrophages of various tissues. Siglec11 is highly homologous to Siglec10 over their extracellular domain but not over their cytoplasmic domain, suggesting that Siglec11 arose through gene duplication followed by a recombination event involving another ancestral siglec gene. Following treatment of Siglec11-transfected cells with pervanadate, Siglec11 becomes tyrosine-phosphorylated and strongly associates with SHP-1 and SHP-2. At least five isoforms of Siglec11 are known to exist. Siglec11 antibody will not cross-react with Siglec10. Despite its predicted size, Siglec11 migrates at a higher than expected molecular weight in SDS-PAGE.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SIGLEC11 antibody

Western blot analysis of Siglec11 in HepG2 cell lysate with Siglec11 antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SIGLEC11 Control Peptide

SIGLEC11
50 µg / €160.00
  Acris Antibodies GmbH

SIGLEC11 antibody

SIGLEC11 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SIGLEC11 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with SIGLEC11 polyclonal antibody ( Cat # PAB3646 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

SIGLEC11 antibody

Immunohistochemistry-Paraffin: SIGLEC11 Antibody [NBP1-77025] - Human liver tissue with Siglec11 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SIGLEC11 overexpression lysate

SIGLEC11 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

SIGLEC11 overexpression lysate

SIGLEC11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SIGLEC11 overexpression lysate

SIGLEC11 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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