SIPA1L1 antibody

Principal name

SIPA1L1 antibody

Alternative names for SIPA1L1 antibody

SIPA1-like protein 1, E6TP1, KIAA0440, Signal-induced proliferation-associated 1-like protein 1, Signal-induced proliferation-associated 1-like protein 1, E6-targeted protein 1

SwissProt ID

O35412 (Rat), O43166 (Human), Q8C0T5 (Mouse)

Gene ID

26037 (SIPA1L1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of SIPA1L1 antibody

Signal-induced proliferation associated-like protein 1 (SIPA1L1) is a member of the SIPA1 family of RapGAPs. SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses. Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1. CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SIPA1L1 antibody

Western blot analysis of SIPA1L1 in rat brain tissue lysate with SIPA1L1 antibody at (A) 0.5 and (B) 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SIPA1L1 (N-term) antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SIPA1L1 Control Peptide

SIPA1L1
50 µg / €160.00
  Acris Antibodies GmbH

SIPA1L1 antibody

Immunohistochemistry-Paraffin: SIPA1L1 Antibody [NBP1-90482] Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in granular pattern in tubular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SIPA1L1 overexpression lysate

SIPA1L1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

5 Item(s)

per page
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