SIX2 antibody

Principal name

SIX2 antibody

Alternative names for SIX2 antibody

Homeobox protein SIX2, Sine oculis homeobox homolog 2

SwissProt ID

Q62232 (Mouse), Q9NPC8 (Human)

Gene ID

10736 (SIX2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ChIP assay (ChIP), Immunoprecipitation (IP), Paraffin Sections (P)

Background of SIX2 antibody

The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence, indicating that they may regulate the same target genes. Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint. Six2 is highly expressed in fetal tissues but expression is limited in adult tissues.

General readings

Weber,S., (2008) J. Am. Soc. Nephrol. 19 (5), 891-903

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SIX2 antibody

Western blot analysis of extracts from HepG2 cells, using SIX2 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SIX2 antibody

WB Suggested Anti-SIX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SIX2 antibody

Immunofluorescence of monoclonal antibody to SIX2 on HeLa cell . [antibody concentration 10 ug/ml] Mouse IgG1 3D7 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SIX2 antibody

SIX2 Mouse IgG1 1G11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SIX2 antibody

Human Muscle; WB Suggested Anti-SIX2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Muscle; SIX2 antibody - N-terminal region (ARP39271_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SIX2

SIX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SIX2

SIX2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SIX2

SIX2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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