SKA3 antibody

Principal name

SKA3 antibody

Alternative names for SKA3 antibody

C13orf3, RAMA1, Spindle and kinetochore-associated protein 3

SwissProt ID

B2GUZ2 (Rat), Q8C263 (Mouse), Q8IX90 (Human)

Gene ID

221150 (SKA3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of SKA3 antibody

Upon entry into mitosis, the cell's microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes. Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs. A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset. Like with SKA1 or SKA2, depletion of SKA3 by siRNA delays anaphase transition, resulting in a prolonged a metaphase-like state. These SKA3-depleted cells accumulate high levels of the checkpoint protein Bub1 at kinetochores, suggesting the SKA complex plays a key role in spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SKA3 antibody

Western blot analysis of SKA3 in human testis tissue lysate with SKA3 antibody at (A) 0.5 and (B) 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SKA3 antibody

WB Suggested Anti-SKA3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SKA3 (C-term) antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SKA3 Control Peptide

SKA3
50 µg / €160.00
  Acris Antibodies GmbH

SKA3 antibody

SKA3 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SKA3 antibody

Human ACHN; WB Suggested Anti-SKA3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: ACHN cell lysate; SKA3 antibody - middle region (ARP55463_P050) in Human ACHN cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SKA3

SKA3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SKA3 (transcript variant 2)

SKA3 Human > 80 %
Preparation: or Add: Recombint proteins was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

SKA3 overexpression lysate

SKA3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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