SKI antibody

Principal name

SKI antibody

Alternative names for SKI antibody

Ski oncogene, ski oncoprotein, Proto-oncogene c-Ski, v-ski avian sarcoma viral oncogene homolog

SwissProt ID

P12755 (Human), P17863 (Avies), P49140 (Chick), Q02225 (Xenla), Q60698 (Mouse), Q9TUG2 (Horse)

Gene ID

6497 (SKI)

Available reactivities

Hu (Human), Chk (Chicken), Ms (Mouse), Rt (Rat), Xen (Xenopus), Frog

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of SKI antibody

TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SKI antibody

Western blot analysis of Ski in human kidney tissue lysate with Ski antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SKI antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SKI (RC214389, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SKI. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SKI antibody

Figure 2. Formalin-Fixed Paraffin-Embedded (FFPE) on Kidney. Rabbit Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SKI Control Peptide

SKI
50 µg / €160.00
  Acris Antibodies GmbH

SKI antibody

SKI Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SKI antibody

SKI Mouse IgG1 B548M Chk, Frog, Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

SKI antibody

Immunofluorescence of SKI in human kidney tissue with SKI polyclonal antibody ( Cat # PAB12846 ) at 20 µg/ml. Rabbit Hu ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

SKI antibody

ELISA: SKI Antibody [27550002] Rabbit Hu E, IP, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

SKI antibody

Immunofluorescence: SKI Antibody [NBP1-77305] - Human kidney tissue with Ski antibody at 20 u/mL._x000d_ Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SKI overexpression lysate

SKI overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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