SKIL / SnoN antibody

Principal name

SKIL / SnoN antibody

Alternative names for SKIL / SnoN antibody

Ski-like protein, Ski-related protein, Ski-related novel protein N, Ski-related oncogene, SNO, SnoA, Snol

SwissProt ID

P12757 (Human), Q60665 (Mouse)

Gene ID

6498 (SKIL)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of SKIL / SnoN antibody

SnoN, an 80 KDa protein, is a member of ski family of nuclear proto-oncogenes involved in regulation of cellular transformation and differentiation. Primarily expressed in two isoforms, SnoN is localized in cytoplasm in normal tissues and non-tumorigenic primary epithelial cells. In cancer tissues or cells, SnoN is exclusively localized in the nucleus. It plays a vital role in inhibition of cell cycle arrest induced by TGF-. Upon morphological differentiation or cell-cycle arrest, SnoN translocates into the nucleus, binds to Smad2, Smad3, and Smad4 on TGF- -responsive promoters and represses their ability to activate expression of TGF- target genes. It has also been found to mediate transcriptional repression of thyroid hormone receptor, Mad and pRb. Increased expression of SnoN has been detected in many human tumor cell lines suggesting a clinical significance.

General readings

Pearson-White,S. and Crittenden,R.(1997) Nucleic Acids Res. 25 (14), 2930-2937

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SKIL / SnoN antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171) Mouse IgG1 OTI2F6 Purified Can, Hu, Mky, Ms, Rt P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800159) Mouse IgG1 OTI1A6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800160) Mouse IgG1 OTI3F6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800162) Mouse IgG1 OTI3E2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800163) Mouse IgG1 OTI3E9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA800172) Mouse IgG1 OTI2C9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

Western blot analysis of SnoN in A431 cell lysate with SnoN antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SKIL / SnoN antibody

Western blot analysis of extracts from HUVEC cells and Jurkat cells, using SKIL antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SKIL / SnoN antibody

Western Blot: SnoN Antibody [TA337044] - Analysis in human kidney cell lysate in the A) absence and B) presence of immunizing peptide, C) mouse kidney, and D) rat kidney cell lysate, using this antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SKIL / SnoN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SKIL (RC209251, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SKIL. Mouse IgG1 OTI3A7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SKIL (RC209251, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SKIL. Mouse IgG1 OTI2C5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SKIL (RC209251, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SKIL. Mouse IgG1 OTI1H2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SKIL / SnoN (N-term) antibody

Figure 2. Formalin-Fixed Paraffin-Embedded (FFPE) on Lung, Respiratory Epithelium. Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SKIL / SnoN (Isoform SNON, 600-684) antibody

Lung, respiratory epithelium: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SKIL / SnoN antibody

Western blot analysis of SnoN antibody (Cat.-No.: AP20409PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SKIL / SnoN Control Peptide

SKIL / SnoN
50 µg / €160.00
  Acris Antibodies GmbH

SKIL / SnoN antibody

Western Blot analysis of SKIL expression in transfected 293T cell line (H00006498-T01) by SKIL MaxPab polyclonal antibody.

Lane 1: SKIL transfected lysate(75.24 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

SKIL / SnoN antibody

SKIL / SnoN Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

SKIL / SnoN antibody

SKIL / SnoN Mouse IgG2a 1C12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SKIL / SnoN antibody

Western blot analysis of SKIL in human kidney lysate in the A ) absence and B ) presence of immunizing peptide, C ) mouse kidney, and D ) rat kidney lysate. Using SKIL polyclonal antibody ( Cat # PAB0354 ) at 1 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

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