SKP2 / FBXL1 antibody

Principal name

SKP2 / FBXL1 antibody

Alternative names for SKP2 / FBXL1 antibody

S-phase kinase-associated protein 2, Cyclin-A/CDK2-associated protein p45, F-box/LRR-repeat protein 1

SwissProt ID

Q13309 (Human), Q9Z0Z3 (Mouse)

Gene ID

6502 (SKP2), 27401 (Skp2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of SKP2 / FBXL1 antibody

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates 2 transcript variants encoding different isoforms.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SKP2 / FBXL1 (Center) antibody

  Rabbit polyclonal SKP2 Antibody (Center)  
Western blot analysis of SKP2 Antibody (Center) (Cat. #TA325037) in Hela cell line lysates (35ug/lane). SKP2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

SKP2 / FBXL1 antibody

  Rabbit Polyclonal anti-SKP2 Antibody  
Host: Rabbit; Target Name: SKP2; Sample Tissue: Colorectal Tumor lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

SKP2 / FBXL1 antibody

  Rabbit Polyclonal Anti-SKP2/p45 Antibody  
Western blot analysis on 293 cell lysate using SKP2/p45 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SKP2 / FBXL1 antibody

Western blot analysis using SKP2 mouse mAb against truncated Trx-SKP2 recombinant protein (1) and GST-SKP2 (aa1-130) recombinant protein (2). Mouse IgG1 6G9D10 Ascites Hu WB
0.1 ml / €400.00
  Acris Antibodies GmbH

SKP2 / FBXL1 (p45) antibody

Immunohistochemistry (IHC) analyzes of SKP2/p45 antibody (Cat.-No.: AP06317PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SKP2 / FBXL1 (221-425) antibody

Human Prostate (formalin-fixed, paraffin-embedded) stained with SKP2 antibody AP22728PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

SKP2 / FBXL1 (N-term) antibody

SKP2 Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

SKP2 / FBXL1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SKP2/p45 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

SKP2 / FBXL1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SKP2/p45 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

SKP2 - human gene knockout kit via CRISPR

SKP2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SKP2 - human gene knockout kit via CRISPR

SKP2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SKP2 - human gene knockout kit via CRISPR

SKP2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SKP2 - human gene knockout kit via CRISPR

SKP2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Skp2 - mouse gene knockout kit via CRISPR

Skp2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Skp2 - mouse gene knockout kit via CRISPR

Skp2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Skp2 - mouse gene knockout kit via CRISPR

Skp2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Skp2 - mouse gene knockout kit via CRISPR

Skp2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SKP2 / FBXL1 (transcript variant 1)

  Recombinant protein of human S-phase kinase-associated protein 2 (p45) (SKP2), transcript variant 1  
SKP2 / FBXL1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

SKP2 / FBXL1 (N-term HIS tag, transcript variant 1)

  Purified recombinant protein of Human S-phase kinase-associated protein 2 (p45) (SKP2), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug  
SKP2 / FBXL1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SKP2 (mGFP-tagged) - Human S-phase kinase-associated protein 2 (p45) (SKP2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SKP2 (mGFP-tagged) - Human S-phase kinase-associated protein 2 (p45) (SKP2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

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