SLAMF6 antibody

Principal name

SLAMF6 antibody

Alternative names for SLAMF6 antibody

NTBA

SwissProt ID

B2R8X8 (Human)

Gene ID

114836 (SLAMF6)

Ncbi ID

9606, NP_443163

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Immunoprecipitation (IP), Flow Cytometry (F), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB)

Background of SLAMF6 antibody

SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Claus,M., (er) Front. Biosci. 13, 956-965 (2008)

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