SLC22A6 / OAT1 antibody

Principal name

SLC22A6 / OAT1 antibody

Alternative names for SLC22A6 / OAT1 antibody

Organic anion transporter 1, ROAT, PAHT, Solute carrier family 22 member 6, Renal organic anion transporter 1, PAH transporter

SwissProt ID

O35956 (Rat), Q4U2R8 (Human), Q6NYN7 (Danre), Q864Z3 (Bovin), Q8MK48 (Pig), Q8VC69 (Mouse), Q9NQC2 (Human), Q9TSY7 (Rabit)

Gene ID

9356 (SLC22A6), 18399 (Slc22a6), 29509

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), African clawed frog, Ze (Zebrafish), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P)

Background of SLC22A6 / OAT1 antibody

SLC22A6(Solute carrier family 22 (organic anion transporter), member 6), also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. The SLC22A6 gene is mapped on 11q12.3. It plays a central role in renal organic anion transport. Along with OAT3, OAT1 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. The SLC22A6 gene contains 10 exons and spans 8.2 kb. OAT1 functions as organic anion exchanger. When the uptake of one molecule of an organic anion is transported into a cell by an OAT1 exchanger, one molecule of an endogenous dicarboxylic acid (such as glutarate, ketoglutarate, etc) is simultaneously transported out of the cell. PAH uptake in Xenopus oocytes injected with OAT1 mRNA was demonstrated by Race et al.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLC22A6 / OAT1 antibody

Predicted band size: 56 kDa . Positive control: Human fetal kidney tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 3 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SLC22A6 / OAT1 antibody

Predicted band size: 56 kDa . Positive control: Human fetal kidney tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/900 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 3 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SLC22A6 / OAT1 antibody

WB Suggested Anti-SLC22A6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SLC22A6 / OAT1 antibody

WB Suggested Anti-SLC22A6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SLC22A6 / OAT1 antibody

Immunohistochemistry analyzes of SLC22A6 / OAT1 Antibody (Cat.-No AP206696PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SLC22A6 / OAT1 antibody

SLC22A6 / OAT1 Mouse IgG1 1F2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SLC22A6 / OAT1 antibody

Imunohistochemical analysis of human kidney tissue, using SLC22A6 polyclonal antibody ( Cat # PAB8460 ) . Rabbit Hu C
25 µg / €660.00
  Abnova Taiwan Corp.

SLC22A6 / OAT1 antibody

Human Placenta; WB Suggested Anti-SLC22A6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Placenta; SLC22A6 antibody - N-terminal region (ARP41549_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SLC22A6 / OAT1 antibody

Human Lung; WB Suggested Anti-SLC22A6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; SLC22A6 antibody - C-terminal region (ARP41550_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SLC22A6 / OAT1 antibody

SLC22A6 / OAT1 Rabbit IgG Aff - Purified Hu, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

SLC22A6 / OAT1 antibody

SLC22A6 / OAT1 Rabbit Aff - Purified Hu C
25 µg / €630.00
  Funakoshi Co., Ltd.

SLC22A6 / OAT1 antibody

SLC22A6 / OAT1 Rabbit Aff - Purified Hu C
25 µg / €630.00
  Funakoshi Co., Ltd.

CRISPR

Catalog No. Species Donor Vector  

Slc22a6 - mouse gene knockout kit via CRISPR

Slc22a6 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Slc22a6 - mouse gene knockout kit via CRISPR

Slc22a6 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Slc22a6 - mouse gene knockout kit via CRISPR

Slc22a6 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Slc22a6 - mouse gene knockout kit via CRISPR

Slc22a6 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SLC22A6 / OAT1

SLC22A6 / OAT1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SLC22A6 / OAT1

SLC22A6 / OAT1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SLC22A6 overexpression lysate

SLC22A6 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

SLC22A6 overexpression lysate

SLC22A6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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