SLC24A2 antibody

Principal name

SLC24A2 antibody

Alternative names for SLC24A2 antibody

NCKX2, Sodium/potassium/calcium exchanger 2, Solute carrier family 24 member 2, Na(+)/K(+)/Ca(2+)-exchange protein 2, Retinal cone Na-Ca+K exchanger

SwissProt ID

O54701 (Rat), Q9IAL7 (Chick), Q9UI40 (Human)

Gene ID

84550 (Slc24a2)

Available reactivities

Rt (Rat), Hu (Human), Mky (Monkey), Ms (Mouse)

Available hosts

Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of SLC24A2 antibody

Sodium/calcium-potassium exchanger proteins (NCKX1) have been reported to occur in retinal photoreceptors and in brain (NCKX2). Unlike the abundant and widely expressed sodium/calcium exchanger which catalyzes the exchange of 3 sodium ions for 1 calcium ion to modulate intracellular calcium levels, NCKX isoforms exchange 4 sodium ions for 1 calcium and 1 potassium ion. The sodium/calcium-potassium exchanger uses the transmembrane sodium gradient to catalyze countertransport of calcium in a potassium-dependent mechanism against its electrochemical gradient. It is hypothesized that NCKX2 plays a significant role in calcium homeostasis and the regulation of neuronal function.

General readings

General / background references:Tsoi M et al. Molecular cloning of a novel potassium-dependent sodium-calcium exchanger from rat brain. J Biol Chem 273:4155-62 (1998). PubMed PMID: 9461611
Schnetkamp PP Calcium homeostasis in vertebrate retinal rod outer segments. Cell Calcium 18:322-30 (1995). PubMed PMID: 8556771
Nicoll DA et al. Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger. Science 250:562-5 (1990). PubMed PMID: 1700476

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLC24A2 antibody

Western blot analysis of NCKX2 expression in HT1080 (A); MCF7 (B); Raw264.7 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

SLC24A2 antibody

Western blot analysis of NCKX2 expression in HT1080 (A); MCF7 (B); Raw264.7 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

SLC24A2 antibody

Western blot analysis of NCKX2 expression in HT1080 (A); MCF7 (B); Raw264.7 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

SLC24A2 antibody

Western Blot: Exchanger (Na/Ca-K) Antibody [NB300-600] - Figure 2 shows a Western blot of NCX2 in rat brain using NB300-600. Rabbit Aff - Purified Rt C, P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SLC24A2 overexpression lysate

SLC24A2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

5 Item(s)

per page
  • LinkedIn