SLC6A12 antibody

Principal name

SLC6A12 antibody

Alternative names for SLC6A12 antibody

BGT-1, Solute carrier family 6 member 12, Sodium- and chloride-dependent betaine transporter, Na(+)/Cl(-) betaine/GABA transporter

SwissProt ID

P27799 (Canfa), P31651 (Mouse), P48055 (Rabit), P48056 (Rat), P48065 (Human)

Gene ID

6539 (SLC6A12), 83633 (Gabbr2)

Available reactivities

Rt (Rat), Hu (Human)

Available hosts

Rabbit, Goat, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F)

Background of SLC6A12 antibody

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl negative channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).

General readings

Conti F, Zucharello LV, Barbaresi P, Minelli A, Brecha NC, Melone M, (1999) Neuronal, glial, and epithelial localization of gamma-aminobutyric acid transporter 2, a high affinity gamma-aminobutyric acid plasma membrane transporter, in the cerebral cortex and neighboring structures. J. Comp Neurol. 409(3): 482-494.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLC6A12 (C-term) antibody

Staining of Human Olfactory bulb lysate using SLC6A12 antibody Cat.-No AP32145PU-N at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence Goat Aff - Purified Hu WB
0.1 mg / €340.00
  Acris Antibodies GmbH

SLC6A12 (N-term) antibody

Western blot analysis in MDA-MB231 cell line lysates (35 µg/lane) using S6A12 Antibody (N-term) Cat.-No AP53785PU-N. This demonstrates the S6A12 antibody detected the S6A12 protein (arrow). Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SLC6A12 antibody

SLC6A12 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SLC6A12 antibody

Western Blot: GABA Transporter 2 Antibody [NB100-61098] - Rat hippocampal homogenate showong specific immunolabeling of the ~67k GAT-3 protein. Rabbit IgG Aff - Purified Rt P
0.1 ml / €380.00
  Novus Biologicals Inc.

SLC6A12 antibody

Immunohistochemistry-Paraffin: SLC6A12 Antibody [NBP1-88641] - Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SLC6A12 overexpression lysate

SLC6A12 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

SLC6A12 overexpression lysate

SLC6A12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SLC6A12 overexpression lysate

SLC6A12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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