SLC6A8 antibody

Principal name

SLC6A8 antibody

Alternative names for SLC6A8 antibody

Creatine transporter 1, CT1, Sodium- and chloride-dependent creatine transporter 1, Solute carrier family 6 member 8

SwissProt ID

O18875 (Bovin), P28570 (Rat), P31661 (Rabit), P48029 (Human), Q8VBW1 (Mouse)

Gene ID

6535 (SLC6A8), 102857 (Slc6a8), 50690

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Eq (Equine), GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of SLC6A8 antibody

Creatine and creatine phosphate are essential for the maintenance of ATP levels in tissues with high and fluctuating energy demands such as skeletal muscle and brain. Creatine kinase catalyzes the reversible transfer of a phosphate from creatine phosphate to ADP regenerating ATP. In mammals, creatine is either synthesized by sequential reactions occurring in the kidney and liver or obtained from the diet. Muscle cells do not synthesize creatine, but take it up via a special sodium-dependent transporter, the creatine transporter (CRT). Inhibition of creatine transport in experimental animals causes muscle weakness. A specific uptake system for creatine has been demonstrated in skeletal muscle, human monocytes, macrophages, and astroglial-rich cultures. CRT exhibits significant homology to the Na(+) and Cl(-) dependent GABA/norepinephrine (GAT-1/norepinephrine transporter) gene family of neurotransmitter transporters. All members of this family are predicted to contain 12-membrane-spanning domains, to contain a large extracellular loop containing sites for N-linked glycosylation between the third and fourth transmembrane domains, and to have the amino and carboxyl termini facing the cytoplasmic side of the membrane. At least two CRT have been cloned and expressed and characterized. CRT1 or CT1 (mouse, human 635 aa, chromosome X28) is expressed in kidney, muscle, brain, and other tissues, while CT2 (human 426-aa, chromosome 16p11.2) is testis specific.

General readings

Dodd,J.R. (2005) J. Biol. Chem. 280 (38), 32649-32654

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLC6A8 antibody

(0.1ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SLC6A8 antibody

Western blot analysis of extracts from HuvEc cells, using SLC6A8 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SLC6A8 antibody

WB Suggested Anti-SLC6A8 Antibody Titration: 2.5 ug/ml; Positive Control: MDA-MB-435S cell lysate; SLC6A8 is strongly supported by BioGPS gene expression data to be expressed in Human MDA-MB435 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SLC6A8 antibody

WB Suggested Anti-SLC6A8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Small Intestine Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SLC6A8 antibody

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (SLC6A8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SLC6A8 antibody

Human Muscle; Rabbit Anti-SLC6A8 Antibody. Catalog Number: ARP42248. Paraffin Embedded Tissue: Human Muscle. Cellular Data: Skeletal muscle cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; SLC6A8 antibody - N-terminal region (ARP42248_T100) in Human Muscle cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

SLC6A8 antibody

Human Small Intestine; WB Suggested Anti-SLC6A8 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Small Intestine; SLC6A8 antibody - middle region (ARP42249_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

SLC6A8 antibody

Western blot analysis of SLC6A8 expression in MDAMB435 (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

SLC6A8 antibody

Western blot analysis of SLC6A8 expression in MDAMB435 (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

SLC6A8 antibody

Western blot analysis of SLC6A8 expression in MDAMB435 (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

Slc6a8 - mouse gene knockout kit via CRISPR

Slc6a8 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Slc6a8 - mouse gene knockout kit via CRISPR

Slc6a8 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Slc6a8 - mouse gene knockout kit via CRISPR

Slc6a8 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Slc6a8 - mouse gene knockout kit via CRISPR

Slc6a8 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SLC6A8

SLC6A8 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SLC6A8 (mGFP-tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC6A8 (mGFP-tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SLC6A8 (mGFP-tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC6A8 (mGFP-tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, SLC6A8 (mGFP-tagged)-Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC6A8 (mGFP-tagged)-Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SLC6A8 (Myc-DDK tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC6A8 (Myc-DDK tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, SLC6A8 (Myc-DDK tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC6A8 (Myc-DDK tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

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