SLC6A8 antibody

Principal name

SLC6A8 antibody

Alternative names for SLC6A8 antibody

Creatine transporter 1, CT1, Sodium- and chloride-dependent creatine transporter 1, Solute carrier family 6 member 8

SwissProt ID

O18875 (Bovin), P28570 (Rat), P31661 (Rabit), P48029 (Human), Q8VBW1 (Mouse)

Gene ID

6535 (SLC6A8), 102857 (Slc6a8)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of SLC6A8 antibody

Creatine and creatine phosphate are essential for the maintenance of ATP levels in tissues with high and fluctuating energy demands such as skeletal muscle and brain. Creatine kinase catalyzes the reversible transfer of a phosphate from creatine phosphate to ADP regenerating ATP. In mammals, creatine is either synthesized by sequential reactions occurring in the kidney and liver or obtained from the diet. Muscle cells do not synthesize creatine, but take it up via a special sodium-dependent transporter, the creatine transporter (CRT). Inhibition of creatine transport in experimental animals causes muscle weakness. A specific uptake system for creatine has been demonstrated in skeletal muscle, human monocytes, macrophages, and astroglial-rich cultures. CRT exhibits significant homology to the Na(+) and Cl(-) dependent GABA/norepinephrine (GAT-1/norepinephrine transporter) gene family of neurotransmitter transporters. All members of this family are predicted to contain 12-membrane-spanning domains, to contain a large extracellular loop containing sites for N-linked glycosylation between the third and fourth transmembrane domains, and to have the amino and carboxyl termini facing the cytoplasmic side of the membrane. At least two CRT have been cloned and expressed and characterized. CRT1 or CT1 (mouse, human 635 aa, chromosome X28) is expressed in kidney, muscle, brain, and other tissues, while CT2 (human 426-aa, chromosome 16p11.2) is testis specific.

General readings

Dodd,J.R. (2005) J. Biol. Chem. 280 (38), 32649-32654

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLC6A8 antibody

(0.1ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SLC6A8 antibody

Western blot analysis of extracts from HuvEc cells, using SLC6A8 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SLC6A8 antibody

Human Muscle; Rabbit Anti-SLC6A8 Antibody. Catalog Number: ARP42248. Paraffin Embedded Tissue: Human Muscle. Cellular Data: Skeletal muscle cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; SLC6A8 antibody - N-terminal region (ARP42248_T100) in Human Muscle cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

SLC6A8 antibody

Human Small Intestine; WB Suggested Anti-SLC6A8 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Small Intestine; SLC6A8 antibody - middle region (ARP42249_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

SLC6A8 antibody

Western blot analysis of SLC6A8 expression in MDAMB435 (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

SLC6A8 antibody

Western blot analysis of SLC6A8 expression in MDAMB435 (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

SLC6A8 antibody

Western blot analysis of SLC6A8 expression in MDAMB435 (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

SLC6A8 antibody

Western Blot: SLC6A8 Antibody [NBP1-60082] - This Anti-SLC6A8 antibody was used in Western Blot of MDA-MB-435S tissue lysate at a concentration of 2.5ug/ml. Rabbit Purified Can, Hu, Ms, Rt P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

SLC6A8 antibody

SLC6A8 Rabbit Purified Hu, Ms, Rt P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

SLC6A8 antibody

Immunohistochemistry-Paraffin: SLC6A8 Antibody [NBP1-85442] - Immunohistochemistry-Paraffin: SLC6A8 Antibody [NBP1-85442] Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SLC6A8

SLC6A8 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

11 Item(s)

per page
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