SLC9A2 / NHE2 antibody

Principal name

SLC9A2 / NHE2 antibody

Alternative names for SLC9A2 / NHE2 antibody

NHE-2, Sodium/hydrogen exchanger 2, Solute carrier family 9 member 2, Na(+)/H(+) exchanger 2

SwissProt ID

P48763 (Rat), P50482 (Rabit), Q9UBY0 (Human)

Gene ID

6549 (SLC9A2), 24783 (Slc9a2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of SLC9A2 / NHE2 antibody

In order to function in optimal conditions, cells must maintain a close to neutral intracellular pH. They have adopted various mechanisms in order to do so, one of which is via +/H+ exchangers (NHEs). Genes belonging to this group are expressed along a very broad range of organisms and are essential for protecting cells against intracellular acidification.To date, nine genes have been identified in mammals; NHE1-9. These membrane proteins have 10-12 transmembrane domains depending on whether a splice variant is expressed and an intracellular N-termil. The C-termil domain can be either intracellular or extracellular, also depending whether a splice variant of the protein is involved. The C-termil part of the protein also undergoes posttranslatiol modification such as phosphorylation. Both NHE-1 and NHE-2 have an extracellular loop which is glycosylated.Under physiological conditions, the +/H+ exchanger mediates the exchange of one extracellular + ion for one intracellular proton, thereby keeping the overall charge neutral1. The extracellular binding site of + is not selective as it can also bind Li+ and H+,K+ ions inhibit NHE-1 but have no effect on NHE-2.The activation of NHE-1 and NHE-2 is sensitive to intracellular acidic pH. Under physiological conditions, both exchangers are not active and upon a drop of intracellular pH, they are rapidly activated.NHE-2 is detected in the intestine, kidney and parietal cells.It is also detected in skeletal muscle and testis.

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLC9A2 / NHE2 antibody

Western blot analysis of rat kidney membranes (lanes 1 and 4), mouse kidney lysate (lanes 2 and 5) and rat stomach lysate (lanes 3 and 6): 1-3. Anti-Na+/H+ Exchanger 2 (NHE-2) antibody , (1:200). 4-6. Anti-Na+/H+ Exchanger 2 (NHE-2) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

SLC9A2 overexpression lysate

SLC9A2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SLC9A2 (mGFP-tagged) - Human solute carrier family 9 (sodium/hydrogen exchanger), member 2 (SLC9A2), 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC9A2 (mGFP-tagged) - Human solute carrier family 9 (sodium/hydrogen exchanger), member 2 (SLC9A2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SLC9A2 (Myc-DDK tagged) - Human solute carrier family 9 (sodium/hydrogen exchanger), member 2 (SLC9A2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC9A2 (Myc-DDK tagged) - Human solute carrier family 9 (sodium/hydrogen exchanger), member 2 (SLC9A2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Slc9a2 (GFP-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc9a2 (GFP-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, Slc9a2 (GFP-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc9a2 (GFP-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,380.00
  OriGene Technologies, Inc.

Lenti ORF particles, Slc9a2 (Myc-DDK-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc9a2 (Myc-DDK-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,377.00
  OriGene Technologies, Inc.

Lenti ORF particles, Slc9a2 (Myc-DDK-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc9a2 (Myc-DDK-tagged ORF) - Rat solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,238.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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