SLFN14 antibody

Principal name

SLFN14 antibody

Alternative names for SLFN14 antibody

Schlafen family member 14

Gene ID

342618 (SLFN14)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SLFN14 antibody

Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.

General readings

1. Schwarz DA, Katamaya CD, and Hedrick SM. Schlafen, a new family of growth regulatory genes that affect thymocyte development. Immunity 1998; 9:657-68.
2. Bustos O, Naik S, Ayers G, et al. Evolution of the Schl
fen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence. Gene 2009; 447:1-11.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLFN14 antibody

Western blot analysis of SLFN14 in mouse kidney tissue lysate with SLFN14 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SLFN14 Control Peptide

50 µg / €160.00
  Acris Antibodies GmbH


Catalog No.    

SLFN14 overexpression lysate

SLFN14 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

3 Item(s)

per page
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