SLIT2 antibody

Principal name

SLIT2 antibody

Alternative names for SLIT2 antibody

SLIT-2, SLIL3, Slit homolog 2 protein

SwissProt ID

O94813 (Human), Q9R1B9 (Mouse), Q9WVC1 (Rat)

Gene ID

9353 (SLIT2), 20563 (Slit2)

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), Xen (Xenopus), Can (Canine)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunoprecipitation (IP)

Background of SLIT2 antibody

SLIT-2 is thought to act as a molecular guidance cue in cellular migration, and its function appears to be mediated by interaction with roundabout homologue receptors. SLIT-1 and SLIT-2 seem to be essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development SLIT-2 may play role in guiding commissural axons once they reach the floor plate by modulating the response to netrin. In vitro, SLIT-2 silences the attractive effect of NTN1 but not its growthstimulatory effect and silencing requires the formation of a ROBO1-DCC complex. In vitro, only commissural axons that crossed the midline responded to SLIT-2. In the developing visual system this protein functions as a repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. SLIT-2 is a secreted protein predominantly expressed in fetal lung and kidney, and adult spinal cord. Weak expression is observed in adult adrenal gland, thyroid, trachea and other tissues examined. Multiple isoforms have been reported for this product.

General readings

Lin L, Rao Y, Isacson O. , Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. ,Mol Cell Neurosci. 2005 Mar;28(3):547-55. , PMID: 15737744

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SLIT2 (C-term) antibody

Human Prostate Carcinoma stained with SLIT2 Antibody Cat.-No AM21041PU (Clone SP122). Rabbit IgG SP122 Purified Hu, Ms F, P
0.5 ml / €510.00
  Acris Antibodies GmbH

SLIT2 (C-term) antibody

Human Prostate Carcinoma stained with SLIT2 Antibody Cat.-No AM21041PU (Clone SP122). Rabbit IgG SP122 Purified Hu, Ms F, P
1 ml / €730.00
  Acris Antibodies GmbH

SLIT2 (C-term) antibody

Human Prostate Carcinoma stained with SLIT2 Antibody Cat.-No AM21041PU (Clone SP122). Rabbit IgG SP122 Purified Hu, Ms F, P
0.1 ml / €290.00
  Acris Antibodies GmbH

SLIT2 antibody

AP22401PU-N SLIT2 antibody staining of Human prostate adenocarcinoma. Rabbit IgG Aff - Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

SLIT2 antibody

AP22401PU-N SLIT2 antibody staining of Human prostate adenocarcinoma. Rabbit IgG Aff - Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

SLIT2 antibody

AP22401PU-N SLIT2 antibody staining of Human prostate adenocarcinoma. Rabbit IgG Aff - Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

SLIT2 antibody

TA311312 (4ug/ml) staining of paraffin embedded Human Spinal Cord. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Goat Aff - Purified Can, Hu, Ms, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

SLIT2 (484-500) antibody

WB using Anti-SLIT-2 antibody shows detection of a band at ~165 kDa (lane 1) corresponding to SLIT-2 present in a chicken spinal cord whole cell lysate (arrowhead). The primary antibody diluted to 1:1,350. Reaction occurred overnight at 4° C followed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX  for 45 min at RT. Molecular weight estimation was made by comparison to prestained MW markers in lane M (700 nm channel, red). Rabbit IgG Aff - Purified Bov, Chk, Hu, Ms, Rt, Tetraodon nigroviridis, Xen E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SLIT2 antibody

SLIT2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SLIT2 antibody

Western blot using SLIT2 polyclonal antibody ( Cat # PAB11259 ) shows detection of a band at ~165 kDa ( lane 1 ) corresponding to SLIT2 present in a chicken spinal cord whole cell lysate ( arrowhead ).
Approximately 30 µg of lysate was separated on a 4-20% Tris-Glycine gel by SDS-PAGE and transferred onto nitrocellulose.
After blocking the membrane was probed with the primary antibody diluted to 1 : 1,350.
Reaction occurred overnight at 4°C followed by washes and reaction with a 1 : 10,000 dilution of IRDyeTM800 conjugated Gt-a-Rabbit IgG [H&L] MX for 45 min at room temperature ( 800 nm channel, green ).
Molecular weight estimation was made by comparison to prestained MW markers in lane M ( 700 nm channel, red ).
IRDyeTM 800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR.
IRDye is a trademark of LI-COR, Inc. Rabbit Bov, Chk, Hu, Ms, Rt E, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

SLIT2 antibody

Immunohistochemistry-Paraffin: SLIT2 Antibody [NB100-40807] - (4ug/ml) staining of paraffin embedded Human Spinal Cord. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Goat IgG Aff - Purified Hu E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

SLIT2 antibody

Immunocytochemistry: SLIT2 Antibody [NB600-881] - Western blot using NB600-881 Purified anti-SLIT-2 antibody shows detection of a band at ~165 kDa (Lanes 1) corresponding to SLIT-2 present in a chicken spinal cord whole cell lysate (arrowhead). Approximately 30 ug of lysate was separated on a 4-20% Tris-Glycine gel by SDSPAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:1,350. Reaction occurred overnight at 4 degrees C followed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX for 45 min at room temperature (800 nm channel, green). Molecular weight estimation was made by comparison to prestained MW markers in lane M (700 nm channel, red). Rabbit IgG Aff - Purified Bov, Chk, Hu, Ms, Rt, Xen E, WB
0.1 mg / €510.00
  Novus Biologicals Inc.

SLIT2 antibody

Immunohistochemistry-Paraffin: SLIT2 Antibody [NBP1-80742] Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

SLIT2 antibody

Immunohistochemistry-Paraffin: Slit2 Antibody (EPR2771) [NBP1-95282] human fetal kidney tissue using anti-Slit2. Rabbit EPR2771 Purified Hu, Ms, Rt IP, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SLIT2

SLIT2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SLIT2

SLIT2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 25 µg / €399.00

Special Price: 25 µg / €239.00

  OriGene Technologies, Inc.

SLIT2

SLIT2 Human Purified > 98 % by SDS-PAGE gel and HPLC analyses HEK293 cells
25 µg / €220.00
  Acris Antibodies GmbH

SLIT2

SLIT2 Human Purified > 98 % by SDS-PAGE gel and HPLC analyses HEK293 cells
5 µg / €140.00
  Acris Antibodies GmbH

SLIT2

SLIT2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SLIT2

SLIT2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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