SMARCB1 antibody

Principal name

SMARCB1 antibody

Alternative names for SMARCB1 antibody

Integrase interactor 1 protein, INI1, SNF5 homolog, SNF5L1, BAF47, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, BRG1-associated factor 47

SwissProt ID

P18480 (Yeast), Q09699 (Schpo), Q12824 (Human), Q5BIN2 (Bovin), Q5U379 (Danre), Q5ZK40 (Chick), Q6GQ82 (Xenla), Q9Z0H3 (Mouse)

Gene ID

6598 (SMARCB1), 20587 (Smarcb1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), African clawed frog, Rt (Rat), Chk (Chicken), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of SMARCB1 antibody

Core component of the BAF (hSWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers. Stimulates in vitro the remodeling activity of SMARCA4/BRG1/BAF190A. Involved in activation of CSF1 promoter. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Plays a key role in cell-cycle control and causes cell cycle arrest in G0/G1. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

General readings

Mueller,W., et al., (2004) Neuropathol Appl Neurobiol 30 (3), 304-307

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SMARCB1 (81-181) antibody

Formalin-Fixed, Paraffin-Embedded Human Colon stained with Anti-SMARCB1 antibody at 10 ug/ml. Mouse IgG1 3E10 Purified Hu, Ms, Rt E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

SMARCB1 antibody

Immunoperoxidase of purified MaxPab antibody to SMARCB1 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), ICC/IF, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between SMARCB1 and BAZ1B. Huh7 cells were stained with anti-SMARCB1 rabbit purified polyclonal 1:1200 and anti-BAZ1B mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SMARCB1 antibody

Immunoperoxidase of monoclonal antibody to SMARCB1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3ug/ml] Mouse IgG1 3E10 Purified Hu, Ms, Rt E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 monoclonal antibody (M02), clone 3E3. Western Blot analysis of SMARCB1 expression in NIH/3T3(Cat # L018V1 ). Mouse IgG1 3E3 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

  Rabbit anti-SMARCB1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using SMARCB1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

SMARCB1 antibody

  Rabbit Polyclonal Anti-SMARCB1 Antibody  
WB Suggested Anti-SMARCB1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

SMARCB1 antibody

  Rabbit Polyclonal Anti-SMARCB1 Antibody  
WB Suggested Anti-SMARCB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysateSMARCB1 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SMARCB1 antibody

  Rabbit Polyclonal Anti-SMARCB1 Antibody  
Host: Rabbit; Target Name: SMARCB1; Sample Tissue: Lymph Node Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SMARCB1 antibody

  Rabbit Polyclonal Anti-SMARCB1 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Jurkat cells, K562 cells, hepg2 cells, Primary antibody: (SMARCB1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SMARCB1 antibody

Formalin-Fixed, Paraffin-Embedded Human astrocytoma stained with INI1 antibody Cat.-No. AM10099SU-N using peroxidase conjugate and DAB chromogen. Note the nuclear staining of malignant glial cells. Mouse IgG2a 25 Supernatant Hu P
1 ml / €590.00
  Acris Antibodies GmbH

SMARCB1 antibody

SMARCB1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 MaxPab rabbit polyclonal antibody. Western Blot analysis of SMARCB1 expression in mouse intestine. Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

SMARCB1 antibody

Western Blot analysis of SMARCB1 expression in transfected 293T cell line (H00006598-T02) by SMARCB1 MaxPab polyclonal antibody.

Lane 1: SMARCB1 transfected lysate(44.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 monoclonal antibody (M03), clone 3C4 Western Blot analysis of SMARCB1 expression in Hela NE ( Cat # L013V3 ). Mouse IgG2b 3C4 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 monoclonal antibody (M04), clone 3H3 Western Blot analysis of SMARCB1 expression in Hela NE ( Cat # L013V3 ). Mouse IgG2b 3H3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 monoclonal antibody (M06), clone 2A3. Western Blot analysis of SMARCB1 expression in Hela NE(Cat # L013V3 ). Mouse IgG2b 2A3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 Mouse IgG2a 3F11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 monoclonal antibody (M12), clone 2D10. Western Blot analysis of SMARCB1 expression in human ovary cancer. Mouse IgG2b 2D10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SMARCB1 antibody

SMARCB1 Mouse IgG2b 3B9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

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