SMC1A / SMC1 antibody

Principal name

SMC1A / SMC1 antibody

Alternative names for SMC1A / SMC1 antibody

SMC protein 1A, SMC-1A, SMC-1-alpha, SMC1L1, DXS423E, Structural maintenance of chromosomes protein 1A, SB1.8

SwissProt ID

O93308 (Xenla), O97593 (Bovin), Q14683 (Human), Q9CU62 (Mouse), Q9Z1M9 (Rat)

Gene ID

8243 (SMC1A)

Available reactivities

Hu (Human), Ms (Mouse), Xen (Xenopus), Prim (Primate), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F)

Background of SMC1A / SMC1 antibody

Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromosome proteins are conserved in eukaryotes and can lead to mitotic chromosome segregation defects, suggesting a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. A number of cellular factors interact with hSMC1/hSMC3 during cell cycle. The major population of hSMC1/hSMC3 is in a compex with hRAD21 forming the human cohesion complex. Human cohesion complex associates with chromosomes which peaks at S phase and dissociates from chromosomes during G2/M transition. In addition, a subpopulation of hSMC1/hSMC3 associates tightly with nuclear matrix and centrosomes during interphase. A subset of hSMC1/hSMC3 is localized to spindle poles, spindles and kinetochores during mitosis when cohesin is in the cytoplasm. hSMC1/hSMC3 is required for spindle aster formation in vitro and reacts with nuclear mitotic apparatus protein in vivo.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SMC1A / SMC1 pSer957 antibody

Staining of formalin fixed, paraffin embedded inflamed oral mucosa with Goat anti Human beta defensin-1 (AP05879PU-N) Rabbit IgG Purified Hu IP, P, WB
0.1 mg / €580.00
  Acris Antibodies GmbH

SMC1A / SMC1 antibody

Immunohistochemistry-Paraffin: SMC1 Antibody (5B6) [NBP1-51596] - Immunohistochemical analysis of paraffin-embedded human colon using SMC1 mouse mAb with DAB staining. Mouse IgG1 5B6 Purified Hu E, F, ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

SMC1A / SMC1 antibody

Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA308965 diluted at 1:5000 Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SMC1A / SMC1 antibody

Western blot analysis of extracts from 293 cells, treated with UV 15', using SMC1 (Ab-957) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SMC1A / SMC1 antibody

Predicted band size: 143 kDa . Positive control: Jurkat cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SMC1A / SMC1 antibody

Western blot analysis of SMC1 expression in UV treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SMC1A / SMC1 antibody

Western blot detection of SMC1A(N-terminus) in HelaNE,Jurkat and A431 cell lysates using SMC1A (N-terminus) mouse mAb (1:1000 diluted).Predicted band size: 143KDa.Observed band size: 143KDa. Mouse IgG1 8E6-A4-F3 Purified F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SMC1A / SMC1 antibody

Western blot detection of SMC1A(C-term) in MOLT-4,U87 MG and HelaNE cell lysates using SMC1A (N-terminus) mouse mAb (1:1000 diluted).Predicted band size: 143KDa.Observed band size: 143KDa. Mouse IgG1 4C5-C8-A11 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SMC1A / SMC1 antibody

Figure 1. Western blotting using SMC1 antibody (AM05298PU-N) on HeLa cell lysate at 1 µg/ml. Mouse C2M Purified Hu ICC/IF, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

SMC1A / SMC1 antibody

SMC1A / SMC1 Mouse IgG1 5B6 Ascites Hu F, ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

SMC1A / SMC1 antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1B9 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

SMC1A / SMC1 pSer957 antibody

Immunohistochemistry (IHC) analysis of SMC1 pSer957 antibody (Cat.-No.: AP01685PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SMC1A / SMC1 pSer957 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using SMC1 (phospho-Ser957) antibody AP02467PU. Rabbit Aff - Purified Hu, Ms P
0.1 ml / €320.00
  Acris Antibodies GmbH

SMC1A / SMC1 pSer957 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using SMC1 (phospho-Ser957) antibody AP02467PU. Rabbit Aff - Purified Hu, Ms P
50 µl / €240.00
  Acris Antibodies GmbH

SMC1A / SMC1 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SMC1 antibody AP02703PU. Rabbit Aff - Purified Hu, Ms P
0.1 ml / €270.00
  Acris Antibodies GmbH

SMC1A / SMC1 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SMC1 antibody AP02703PU. Rabbit Aff - Purified Hu, Ms P
50 µl / €230.00
  Acris Antibodies GmbH

SMC1A / SMC1 pSer966 antibody

Detection of human phospho-SMC1 (pSER966) in whole cell lysates of HeLa cells subjected to 10Gy gamma irradiation by Western blotting using Rabbit anti Human phospho-SMC1 (pSER966) (AP05757PU-N) Rabbit IgG Purified Hu IP, WB
0.1 mg / €610.00
  Acris Antibodies GmbH

SMC1A / SMC1 antibody

Immunohistochemistry (IHC) analysis of SMC1 antibody (Cat.-No.: AP06318PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P
0.1 mg / €350.00
  Acris Antibodies GmbH

SMC1A / SMC1 antibody

SMC1L1 polyclonal antibody (A01), Lot # 051003JC01 Western Blot analysis of SMC1L1 expression in 293 ( Cat # L026V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SMC1A / SMC1 antibody

Immunoperoxidase of monoclonal antibody to SMC1L1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 1 ug/ml] Mouse IgG1 1B9 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

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