SNIP1 antibody

Principal name

SNIP1 antibody

Alternative names for SNIP1 antibody

Smad nuclear-interacting protein 1, FHA domain-containing protein SNIP1

SwissProt ID

Q8BIZ6 (Mouse), Q8TAD8 (Human)

Gene ID

79753 (SNIP1), 6479753 (B5E670)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of SNIP1 antibody

Members of the transforming growth factor-beta superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-beta family ligands are mediated by Smad proteins. A 396-amino acid nuclear protein termed SNIP1 was cloned and shown to harbor a nuclear localization signal (NLS) and a Forkhead-associated (FHA) domain. The carboxyl terminus of SNIP1 interacts with Smad1 and Smad2 in yeast two-hybrid as well as in mammalian overexpression systems. However, the amino terminus of SNIP1 harbors binding sites for both Smad4 and the coactivator CBP/p300. Overexpression of full-length SNIP1 or its amino terminus is sufficient to inhibit multiple gene responses to TGF-beta and CBP/p300, as well as the formation of a Smad4/p300 complex. Studies in Xenopus laevis further suggest that SNIP1 plays a role in regulating dorsomedial mesoderm formation by the TGF-beta family member nodal. Thus, SNIP1 is a nuclear inhibitor of CBP/p300 and its level of expression in specific cell types has important physiological consequences by setting a threshold for TGF-beta-induced transcriptional activation involving CBP/p300.

General readings

Kim RH, et al. (2000) Genes Dev. 14(13):1605-16.
Kim RH, et al. (2001) J Biol Chem. 276(49):46297-304.

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SNIP1 antibody

WB Suggested Anti-SNIP1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysateSNIP1 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SNIP1 (N-term) antibody

SNIP1 Antibody (N-term) (Cat. #AP53961PU-N) western blot analysis in Jurkat cell line lysates (35µg/lane).This demonstrates the SNIP1 antibody detected the SNIP1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SNIP1 antibody

Immunofluorescence of purified MaxPab antibody to SNIP1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SNIP1 antibody

Immunofluorescence of purified MaxPab antibody to SNIP1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

SNIP1 antibody

Western Blot analysis of SNIP1 expression in transfected 293T cell line (H00079753-T02) by SNIP1 MaxPab polyclonal antibody.

Lane 1: SNIP1 transfected lysate(45.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

SNIP1 antibody

Human Jurkat; WB Suggested Anti-SNIP1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate. SNIP1 is supported by BioGPS gene expression data to be expressed in Jurkat.; SNIP1 antibody - middle region (ARP33585_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SNIP1 antibody

WB and IP: SNIP1 Antibody [NB100-512] - Detection of Human SNIP1 by Western Blot and Immunoprecipitation using NB100-512. Samples: Whole cell lysate from HeLa cells. Chemiluminescence with an exposure time of 30 seconds. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

SNIP1 antibody

Immunohistochemistry-Paraffin: SNIP1 Antibody [NBP1-89428] -  staining of human cerebral cortex shows strong cytopalsmic positivity in glial cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SNIP1 (258-396, His-tag)

SNIP1 Human Purified > 90 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

SNIP1 (258-396, His-tag)

SNIP1 Human Purified > 90 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

SNIP1

SNIP1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

SNIP1 (Human) IP-WB Antibody Pair

SNIP1 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SNIP1 293T Cell Transient Overexpression Lysate(Denatured)

SNIP1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

SNIP1 293T Cell Transient Overexpression Lysate(Denatured)

SNIP1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

14 Item(s)

per page
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