Snurportin-1 (SNUPN) antibody

Principal name

Snurportin-1 (SNUPN) antibody

Alternative names for Snurportin-1 (SNUPN) antibody

Snurportin1, RNUT1, SPN1, KPNBL, RNA U transporter 1

SwissProt ID

O36023 (Schpo), O95149 (Human), Q2TBK8 (Bovin), Q5ZI43 (Chick), Q68FP5 (Rat), Q80W37 (Mouse)

Gene ID

10073 (SNUPN), 66069 (Snupn)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Eq (Equine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP)

Background of Snurportin-1 (SNUPN) antibody

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5\'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5\'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

General readings

Goette, M., et al. Biophys. J. 97(2):581-589 (2009)
Monecke, T., et al. Science 324(5930):1087-1091 (2009)
Ospina, J.K., et al. Mol. Biol. Cell 16(10):4660-4671 (2005)
Stelzl, U., et al. Cell 122(6):957-968 (2005)
Strasser, A., et al. EMBO J. 24(13):2235-2243 (2005)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Snurportin-1 (SNUPN) antibody

  Rabbit Polyclonal Anti-SNUPN Antibody  
WB Suggested Anti-SNUPN Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human heart Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Snurportin-1 (SNUPN) (Center) antibody

Western blot analysis in A375 cell line lysates (35ug/lane) using Snurportin-1 (SNUPN) antibody Cat.-No. AP53970PU-N. This demonstrates the SNUPN antibody detected the SNUPN protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SNUPN - human gene knockout kit via CRISPR

SNUPN - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SNUPN - human gene knockout kit via CRISPR

SNUPN - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SNUPN - human gene knockout kit via CRISPR

SNUPN - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SNUPN - human gene knockout kit via CRISPR

SNUPN - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Snupn - mouse gene knockout kit via CRISPR

Snupn - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Snupn - mouse gene knockout kit via CRISPR

Snupn - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Snupn - mouse gene knockout kit via CRISPR

Snupn - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Snupn - mouse gene knockout kit via CRISPR

Snupn - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Snurportin-1 (SNUPN) (transcript variant 3)

  Recombinant protein of human snurportin 1 (SNUPN), transcript variant 3  
Snurportin-1 (SNUPN) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Snurportin-1 (SNUPN) (transcript variant 1)

  Recombinant protein of human snurportin 1 (SNUPN), transcript variant 1  
Snurportin-1 (SNUPN) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Snurportin-1 (SNUPN) (transcript variant 2)

  Recombinant protein of human snurportin 1 (SNUPN), transcript variant 2  
Snurportin-1 (SNUPN) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Snurportin-1 (SNUPN) (1-360, His-tag)

Snurportin-1 (SNUPN) Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

Snurportin-1 (SNUPN) (1-360, His-tag)

Snurportin-1 (SNUPN) Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

SNUPN overexpression lysate

SNUPN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SNUPN overexpression lysate

SNUPN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SNUPN overexpression lysate

SNUPN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SNUPN overexpression lysate

SNUPN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SNUPN overexpression lysate

SNUPN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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