SOCS2 / CIS2 antibody

Principal name

SOCS2 / CIS2 antibody

Alternative names for SOCS2 / CIS2 antibody

Suppressor of cytokine signaling 2, SOCS-2, CIS-2, SSI2, SSI-2, STATI2, Cytokine-inducible SH2 protein 2, STAT-induced STAT inhibitor 2

SwissProt ID

O14508 (Human), O35717 (Mouse), O88582 (Rat), Q7YRV6 (Pig), Q861R0 (Bovin)

Gene ID

8835 (SOCS2), 216233 (Socs2), 84607

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP)

Background of SOCS2 / CIS2 antibody

Accumulating evidence demonstrates that cytokine receptor signaling is negatively regulated by a family of Src homology 2 domain-containing adaptor molecules Termed SOCS (Suppressor of Cytokine Signaling). To date, there are eight members of SOCS family have been recognized, they are SOCS-1, 2, 3, 4, 5, 6, 7 and CIS. Structurally the SOCS proteins are composed of an N-terminal region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C-terminal motif that we have called the SOCS box. The SOCS proteins appear to form part of a classical negative feed back loop that regulates cytokine signal transduction via a STAT-induced transcriptional mechanism. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways.

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SOCS2 / CIS2 antibody

  Rabbit Polyclonal Anti-SOCS2 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (SOCS2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SOCS2 / CIS2 antibody

  Rabbit Polyclonal anti-SOCS-2 Antibody  
Human Pancreas stained with anti-SOCS-2 antibody. Rabbit Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SOCS2 / CIS2 antibody

  Rabbit Polyclonal SOCS2 Antibody  
ELISA: SOCS2 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

SOCS2 - human gene knockout kit via CRISPR

SOCS2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SOCS2 - human gene knockout kit via CRISPR

SOCS2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SOCS2 - human gene knockout kit via CRISPR

SOCS2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SOCS2 - human gene knockout kit via CRISPR

SOCS2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SOCS2 (mGFP-tagged) - Human suppressor of cytokine signaling 2 (SOCS2), 200 uL, >10^7 TU/mL

Lenti ORF particles, SOCS2 (mGFP-tagged) - Human suppressor of cytokine signaling 2 (SOCS2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SOCS2 (Myc-DDK tagged) - Human suppressor of cytokine signaling 2 (SOCS2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, SOCS2 (Myc-DDK tagged) - Human suppressor of cytokine signaling 2 (SOCS2) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Socs2 (GFP-tagged) - Mouse suppressor of cytokine signaling 2 (Socs2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Socs2 (GFP-tagged) - Mouse suppressor of cytokine signaling 2 (Socs2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Socs2 (Myc-DDK-tagged) - Mouse suppressor of cytokine signaling 2 (Socs2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Socs2 (Myc-DDK-tagged) - Mouse suppressor of cytokine signaling 2 (Socs2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Socs2 (GFP-tagged ORF) - Rat suppressor of cytokine signaling 2 (Socs2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Socs2 (GFP-tagged ORF) - Rat suppressor of cytokine signaling 2 (Socs2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Socs2 (Myc-DDK-tagged ORF) - Rat suppressor of cytokine signaling 2 (Socs2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Socs2 (Myc-DDK-tagged ORF) - Rat suppressor of cytokine signaling 2 (Socs2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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