SOCS7 / NAP4 antibody

Principal name

SOCS7 / NAP4 antibody

Alternative names for SOCS7 / NAP4 antibody

Suppressor of cytokine signaling 7, SOCS-7, NAP-4, SOCS6, Nck Ash and phospholipase C gamma-binding protein, Nck-associated protein 4

SwissProt ID

O14512 (Human), Q8VHQ2 (Mouse)

Gene ID

30837 (SOCS7)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Por (Porcine), Rb (Rabbit), Can (Canine), Eq (Equine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of SOCS7 / NAP4 antibody

SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

General readings

Kremer BE, Adang LA, Macara IG.
Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.
Cell. 2007 Sep 7;130(5):837-50.
PMID: 17803907

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SOCS7 / NAP4 antibody

TA305889 (1ug/ml) staining of Daudi lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SOCS7 / NAP4 antibody

Predicted cell location: Cytoplasm,Nucleus. Positive control: Human liver and lung cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using SOCS7 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SOCS7 / NAP4 antibody

Predicted cell location: Cytoplasm,Nucleus. Positive control: Human liver and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using SOCS7 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SOCS7 / NAP4 antibody

WB Suggested Anti-SOCS7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: OVCAR-3 cell lysate. SOCS7 is supported by BioGPS gene expression data to be expressed in OVCAR3 Rabbit IgG Purified Bov, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SOCS7 / NAP4 antibody

Host: Rabbit; Target Name: SOCS7; Sample Tissue: Breast Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SOCS7 / NAP4 antibody

SOCS7 / NAP4 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SOCS7 / NAP4 antibody

SOCS7 polyclonal antibody ( Cat # PAB11463 ) ( 1 µg/ml ) staining of Daudi lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SOCS7 / NAP4 antibody

Human OVCAR-3; WB Suggested Anti-SOCS7 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: OVCAR-3 cell lysate. SOCS7 is supported by BioGPS gene expression data to be expressed in OVCAR3.; SOCS7 antibody - N-terminal region (ARP53700_P050) in Human OVCAR-3 cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SOCS7 / NAP4 antibody

SOCS7 / NAP4 Rabbit Hu E, P, WB
50 µg / €400.00
  Novus Biologicals Inc.

SOCS7 / NAP4 antibody

Western Blot: SOCS7 Antibody [NBP1-06994]- (1µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

SOCS7 / NAP4 antibody

Western Blot: SOCS7 Antibody [NBP1-58902] - This Anti-SOCS7 antibody was used in Western Blot of OVCAR-3     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SOCS7 / NAP4

SOCS7 / NAP4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SOCS7 / NAP4

SOCS7 / NAP4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SOCS7 overexpression lysate

SOCS7 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

14 Item(s)

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