Sorting nexin-2 (SNX2) antibody

Principal name

Sorting nexin-2 (SNX2) antibody

Alternative names for Sorting nexin-2 (SNX2) antibody

TRG9, TRG-9, Transformation-related gene 9 protein

SwissProt ID

O60749 (Human), Q2TBW7 (Bovin), Q9CWK8 (Mouse)

Gene ID

6643 (SNX2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Chicken

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Sorting nexin-2 (SNX2) antibody

Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor and facilitate its transport to lysosome, thereby contributing to the degradation of the receptor. SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes and they likewise associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multi-subunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.

General readings

Skanland, S.S., et al. Traffic 8(3):297-309 (2007)
Rojas, R., et al. Mol. Cell. Biol. 27(3):1112-1124 (2007)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292 (2006)
Carlton, J.G., et al. J. Cell. Sci. 118 (PT 19), 4527-4539 (2005)
Abdul-Ghani, M., et al. J. Cell. Physiol. 204(1):210-218 (2005)

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Sorting nexin-2 (SNX2) (C-term) antibody

Western blot analysis in A375 cell line lysates (35ug/lane) using Sorting nexin-2 (SNX2) antibody Cat.-No. AP53974PU-N. This demonstrates the SNX2 antibody detected the SNX2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Sorting nexin-2 (SNX2)

Sorting nexin-2 (SNX2) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Sorting nexin-2 (SNX2)

Sorting nexin-2 (SNX2) Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.


Catalog No.    

SNX2 overexpression lysate

SNX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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