SOS1 antibody

Principal name

SOS1 antibody

Alternative names for SOS1 antibody

SOS-1, Son of sevenless homolog 1

SwissProt ID

Q07889 (Human), Q62245 (Mouse)

Gene ID

6654 (SOS1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of SOS1 antibody

The guanine nucleotide exchange factor Sos (Son-of-sevenless) is a complex multidomain protein that activates the small GTPase Ras (H-Ras, K-Ras, N-Ras, but not functionally distinct R-Ras) in response to receptor tyrosine kinase stimulation. Nucleotide exchange activity of Sos is stimulated by allosteric Ras binding. By another (separable) guanine exchange factor domain domain Sos modulates activity of Rac/Rho GTPases. Sos thus integrates signals that affect both gene expression and cytoskeletal reorganization; the Sos-mediated Ras-activation and Rac activation differ in composition and stability of the formed complex.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SOS1 antibody

Host: Rabbit; Target Name: Sos1; Sample Tissue: Mouse Spleen lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SOS1 antibody

Figure 3. Immunofluorescence staining of Sos in murine transformed fibroblasts using anti-Sos (SOS-01; red). Actin cytoskeleton was decorated by phalloidin (green) and cell nuclei stained with DAPI (blue). Mouse IgG1 SOS-1 Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

SOS1 (1186-1200) antibody

Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hu, Mky, Ms, Prim, Rb P
50 µg / €470.00
  Acris Antibodies GmbH

SOS1 antibody

SOS1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SOS1 antibody

SOS1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SOS1 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between GAB1 and SOS1. Mahlavu cells were stained with anti-GAB1 rabbit purified polyclonal 1:1200 and anti-SOS1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2a 4C1 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

SOS1 antibody

Fig. A : Immunofluorescence staining of SOS1 in human primary fibroblasts using SOS1 monoclonal antibody, clone SOS-01 ( Cat # MAB3649 ; green ). Actin cytoskeleton was decorated by phalloidin ( red ) and cell nuclei stained with DAPI ( blue ).
Fig. B : Immunofluorescence staining of SOS1 in murine transformed fibroblasts using SOS1 monoclonal antibody, clone SOS-01 ( Cat # MAB3649 ; red ). Actin cytoskeleton was decorated by phalloidin (green) and cell nuclei stained with DAPI (blue). Mouse IgG1 SOS-01 Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

SOS1 antibody

Immunoblot analysis of cell lysates.
Lane 1 : HeLa.
Lane 2 : Molt 4.
Lane 3 : HepG2.
Lane 4 : NIH/3T3.
Lane 5 : PC-12. Mouse IgG1 AF3F11 Purified Hu, Ms, Rt E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

SOS1 antibody

Immunocytochemistry: SOS1 Antibody (SOS-01) [NB110-68800] -  Immunofluorescence staining of Sos in human primary fibroblasts using anti-Sos (SOS-01; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue). Mouse IgG1 SOS-1 Purified Hu, Ms ICC/IF, WB
0.1 mg / €340.00
  Novus Biologicals Inc.

SOS1 antibody

Western Blot: SOS1 Antibody [NBP1-05954]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.  Affinity purified rabbit anti-SOS1 antibody  used for IP at 3 mcg/mg lysate. SOS1 was also immunoprecipitated by rabbit anti-SOS1 antibody NBP1-05955, which recognizes a downstream epitope Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

SOS1 antibody

Western Blot and Immunoprecipitation: SOS1 Antibody [NBP1-05955] - Whole cell lysate from HeLa and 293T cells. SOS1 was also immunoprecipitated by rabbit anti-SOS1 antibody NBP1-05954. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

SOS1 antibody

SOS1 Goat Aff - Purified Hu, Ms, Rt P
50 µg / €480.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SOS1

SOS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

SOS1

SOS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

14 Item(s)

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