SP7 / OSX antibody

Principal name

SP7 / OSX antibody

Alternative names for SP7 / OSX antibody

Transcription factor Sp7, Osterix

SwissProt ID

Q8TDD2 (Human), Q8VI67 (Mouse)

Gene ID

121340 (SP7), 170574 (Sp7)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of SP7 / OSX antibody

OSTERIX, or SP7, is a zinc finger-containing, osteoblast-specific transcription factor that is distinctly expressed in all developing bones, and is a key requirement for the differentiation of pre-osteoblasts into fully functional osteoblasts. While research on the actual functional mechanisms of OSTERIX is still on-going, current findings indicate that OSTERIX expression is induced by BMP-2 and Dlx5, and operates downstream of RUNX2, supporting its role in mesenchymal stem cell differentiation. Further studies also indicate that the OSTERIX transcription factor may also play a role in negatively regulating the Wnt/Beta-catenin signaling pathways and the proliferation of osteroblast cell types during embryonic osteogenesis. LOCATION: Nucleus (By similarity). SIMILARITY: Belongs to the Sp1 C2H2-type zinc-finger protein family.

General readings

Gao Y, Jheon A, Nourkeyhani H, Kobayashi H, Ganss B. Molecular cloning, structure, expression, and chromosomal localization of the human Osterix (SP7) gene. Gene. 2004 Oct 27;341:101-10.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SP7 / OSX antibody

Host: Rabbit; Target Name: Sp7; Sample Tissue: Rat Testis lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SP7 / OSX antibody

WB Suggested Anti-SP7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human kidney Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

SP7 / OSX (220-234) antibody

SP7 / OSX Rabbit Serum Hu E
0.1 ml / €500.00
  Acris Antibodies GmbH

SP7 / OSX (220-234) antibody

SP7 / OSX Rabbit Serum Hu E
20 µl / €170.00
  Acris Antibodies GmbH

SP7 / OSX antibody

SP7 / OSX Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

SP7 / OSX antibody

Detection limit for recombinant GST tagged SP7 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 2G6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SP7 / OSX antibody

SP7 / OSX Mouse IgG2a 1C11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SP7 / OSX antibody

Human Jurkat; WB Suggested Anti-SP7 Antibody. . Titration: 2.5 ug/ml. . Positive Control: Jurkat Whole Cell; SP7 antibody - C-terminal region (ARP31622_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

SP7 / OSX antibody

Human Testis; Immunohistochemistry with Testis tissue at an antibody concentration of 5ug/ml using anti-SP7 antibody (ARP32231_P050); SP7 antibody - N-terminal region (ARP32231_P050) in Human Testis cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SP7 / OSX

SP7 / OSX Human
10 µg / €380.00
  Abnova Taiwan Corp.

SP7 / OSX

SP7 / OSX Human
25 µg / €510.00
  Abnova Taiwan Corp.

SP7 / OSX

SP7 / OSX Human 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

SP7 / OSX

SP7 / OSX Human 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SP7 overexpression lysate

SP7 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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