SPEN antibody

Principal name

SPEN antibody

Alternative names for SPEN antibody

Msx2-interacting protein, MINT, SHARP, KIAA0929, SPEN homolog, SMART/HDAC1-associated repressor protein

SwissProt ID

Q62504 (Mouse), Q96T58 (Human)

Gene ID

23013 (SPEN)

Available reactivities

Hu (Human)

Available hosts

Rabbit, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of SPEN antibody

This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SPEN antibody

SPEN Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

SPEN antibody

Western Blot: SHARP Antibody [NB100-58798] - Detection of Human SHARP by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-SHARP antibody NB100-58798 used for IP at 3 mcg/mg lysate. SHARP was also immunoprecipitated by rabbit anti-SHARP antibody Nb100-58799, which recognizes a downstream epitope.  Detection:  Chemiluminescence with an exposure time of 3 minutes. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

SPEN antibody

Western Blot: SHARP Antibody [NB100-58799] - Detection of Human SHARP by Western Blot of Immunoprecipitates.  Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SHARP antibody NB100-58799 used for IP at 3 mcg/mg lysate. SHARP was also immunoprecipitated by rabbit anti-SHARP antibody NB100-58798, which recognizes an upstream epitope.  Detection: Chemiluminescence with an exposure time of 3 minutes. Rabbit Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

SPEN antibody

Immunohistochemistry-Paraffin: SPEN Antibody [NBP1-82952] - Immunohistochemical staining of human rectum shows strong nuclear and slightly weaker cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

4 Item(s)

per page
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