Spindlin 2B / SPIN2B antibody
Principal name
Spindlin 2B / SPIN2B antibody
Alternative names for Spindlin 2B / SPIN2B antibody
Spindlin-2B, SPIN-2B, SPIN2, SPIN-2, Spindlin-like protein 2B
SwissProt ID
Q9BPZ2 (Human)
Gene ID
474343 (SPIN2B)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of Spindlin 2B / SPIN2B antibody
Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal; but it was uble to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary; SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also; SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-termil amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells; SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M; which was more pronounced following IL3 withdrawal.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA323478 | Spindlin 2B / SPIN2B antibody |
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| Anti-SPIN2B Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€325.00
|
|
| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP310041 | Spindlin 2B / SPIN2B (transcript variant 1) |
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| Recombinant protein of human spindlin family, member 2B (SPIN2B), transcript variant 1 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€680.00
|
|
| OriGene Technologies, Inc. | |||||
| TP313224 | Spindlin 2B / SPIN2B (transcript variant 3) |
||||
| Recombinant protein of human spindlin family, member 2B (SPIN2B), transcript variant 3 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€680.00
|
|
| OriGene Technologies, Inc. | |||||
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC210041L2V | Lenti ORF particles, SPIN2B (mGFP-tagged) - Human spindlin family, member 2B (SPIN2B), transcript variant 1, 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€880.00
|
|
| OriGene Technologies, Inc. | ||
| RC210041L1V | Lenti ORF particles, SPIN2B (Myc-DDK tagged) - Human spindlin family, member 2B (SPIN2B), transcript variant 1 , 200 uL, >10^7 TU/mL |
|
|
200 µl /
€780.00
|
|
| OriGene Technologies, Inc. | ||
