Spindlin 2B / SPIN2B antibody

Principal name

Spindlin 2B / SPIN2B antibody

Alternative names for Spindlin 2B / SPIN2B antibody

Spindlin-2B, SPIN-2B, SPIN2, SPIN-2, Spindlin-like protein 2B

SwissProt ID

Q9BPZ2 (Human)

Gene ID

474343 (SPIN2B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Spindlin 2B / SPIN2B antibody

Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal; but it was uble to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary; SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also; SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-termil amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells; SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M; which was more pronounced following IL3 withdrawal.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Spindlin 2B / SPIN2B antibody

Predicted band size: 29 kDa . Positive control: SP20 cell lysate. Recommended dilution: 1/200-1000. (Gel: 12%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Spindlin 2B / SPIN2B (transcript variant 1)

Spindlin 2B / SPIN2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Spindlin 2B / SPIN2B (transcript variant 3)

Spindlin 2B / SPIN2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SPIN2B (mGFP-tagged) - Human spindlin family, member 2B (SPIN2B), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SPIN2B (mGFP-tagged) - Human spindlin family, member 2B (SPIN2B), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, SPIN2B (Myc-DDK tagged) - Human spindlin family, member 2B (SPIN2B), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SPIN2B (Myc-DDK tagged) - Human spindlin family, member 2B (SPIN2B), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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