Spondin 1 / SPON1 antibody

Principal name

Spondin 1 / SPON1 antibody

Alternative names for Spondin 1 / SPON1 antibody

Spondin-1, F-spondin, VSGP, KIAA0762, Vascular smooth muscle cell growth-promoting factor

SwissProt ID

P35446 (Rat), P35447 (Xenla), Q8VCC9 (Mouse), Q9GLX9 (Bovin), Q9HCB6 (Human), Q9W770 (Chick)

Gene ID

10418 (SPON1), 64456 (Spon1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Mouse, Chicken, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of Spondin 1 / SPON1 antibody

SPON1 is a member of a subgroup of the thrombospondin type 1 (TSR) class molecules, defined by two domains of homology, the FS1/FS2 and TSR domains. The TSRs of SPON1 proteins are typical of class 2 TSRs. SPON1, which is similar to thrombospondin, is a extracellular matrix attached molecule that promotes neurite outgrowth and inhibits angiogenesis. Analysis of gain and loss of function experiments reveal that SPON1 is required for accurate pathfinding of embryonic axons, and plays a dual role in patterning axonal trajectories. It promotes the outgrowth of commissural and inhibits the outgrowth of motor axons, and has also been implicated in inflammatory processes in the nervous system.

General readings

General / background references:Klar A et al. F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell 69:95-110 (1992). PubMed PMID: 1555244

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Spondin 1 / SPON1 (N-term) antibody

VSGP/F-spondin Antibody (N-term) (AP54519PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of VSGP/F-spondin Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Bov, Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Spondin 1 / SPON1 antibody

Spondin 1 / SPON1 Mouse IgG1 3F4 Purified Hu E
50 µg / €370.00
  Abnova Taiwan Corp.

Spondin 1 / SPON1 antibody

Western Blot: E coli-derived fusion protein as test antigen. Affi-anti- SPON1 IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-SPON1 ) Chicken Aff - Purified Hu, Ms, Rt WB
50 µg / €520.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Spondin 1 / SPON1

Spondin 1 / SPON1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Spondin 1 / SPON1

Spondin 1 / SPON1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

5 Item(s)

per page
  • LinkedIn