Sponge Hsp70 antibody

Principal name

Sponge Hsp70 antibody

Alternative names for Sponge Hsp70 antibody

Heat Shock Protein 70

SwissProt ID

Q24952 (Geocy)

Ncbi ID

6047

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP)

Background of Sponge Hsp70 antibody

Heat shock proteins (HSPs) or stress response proteins (SRPs) are synthesized in variety of environmental and pathophysiological stressful conditions. Many HSPs are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion. HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides, and other unknown proteins. Also, HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs, and other damaging conditions.

Heat shock proteins are produced by prokaryotic and eukaryotic cells, and are among the most conserved molecules in phylogeny. Eukaryotic cells contain an HSP70 multigene that differ in their intracellular location and regulation. Members of the HSP70 family play a major role in the folding, unfolding and translocation of polypeptides as well as in the assembly and disassembly of oligomeric protein complexes, as well as in the immune response. HSP72 was found to increase dramatically in the brains of Alzheimer’s disease patients, and was localized exclusively in neuritic plaques and neurofibrillary tangles. HSP70 concentrates in nuclei during heat shock and returns to the cytoplasm when the shock is removed.

General readings

Koziol C, Kruse M, Wagner-Hülsmann C, Pancer Z, Batel R and Müller WEG (1996) Cloning of the heat-inducible stress protein (hsp70) from the marine sponge Geodia cydonium. Canad Technical Rep Fisheries Aquatic Sci 2093: 104-109

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Sponge Hsp70 antibody

a: Extracts from cadmium chloride-exposed Suberites domuncula were separated by size and transferred to membranes. The blots were incubated with antibody IVF5. The arrow head points to the band, representing hsp70.
M: Molecular mass marker proteins Mouse IgG1 IVF5 Purified Geodia cydonium C, E, IP, WB
0.1 mg / €510.00
  Acris Antibodies GmbH

Sponge Hsp70 antibody

a: Extracts from cadmium chloride-exposed Suberites domuncula were separated by size and transferred to membranes. The blots were incubated with antibody IVF5. The arrow head points to the band, representing hsp70.
M: Molecular mass marker proteins Mouse IgG1 IVF5 Purified Geodia cydonium C, E, IP, WB
10 µg / €150.00
  Acris Antibodies GmbH

Sponge Hsp70 antibody

Sponge Hsp70 Rabbit Serum Geodia cydonium C, E, WB
0.1 ml / €500.00
  Acris Antibodies GmbH

Sponge Hsp70 antibody

Sponge Hsp70 Rabbit Serum Geodia cydonium C, E, WB
20 µl / €170.00
  Acris Antibodies GmbH

4 Item(s)

per page
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