SPOP antibody

Principal name

SPOP antibody

Alternative names for SPOP antibody

Speckle-type POZ protein, TEF2, HIB homolog 1, Roadkill homolog 1

SwissProt ID

O43791 (Human), Q0VCW1 (Bovin), Q6ZWS8 (Mouse), Q7T330 (Danre)

Gene ID

8405 (SPOP)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of SPOP antibody

SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.

General readings

Kwon J.E., et al. (2006) J. Biol. Chem. 281:12664-12672.
Furukawa M., et al. (2003) Nat. Cell Biol. 5:1001-1007.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SPOP antibody

WB Suggested Anti-SPOP Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysateSPOP is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SPOP antibody

Immunofluorescence of purified MaxPab antibody to SPOP on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

SPOP antibody

Western Blot analysis of SPOP expression in transfected 293T cell line (H00008405-T02) by SPOP MaxPab polyclonal antibody.

Lane 1: SPOP transfected lysate(42.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SPOP antibody

Detection limit for recombinant GST tagged SPOP is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 3E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SPOP antibody

Hela; Host: Rabbit. Target Name:SPOP. Sample Tissue:Hela. Lane A: Primary Antibody . Lane B: Primary Antibody + Blocking Peptide . Primary Antibody Concentration:1ug/ml. Peptide Concentration: 5ug/ml. Lysate Quantity: 25ug/lane/lane. Gel Concentration: 0.12.; SPOP antibody - C-terminal region (ARP50348_P050) in Hela cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

SPOP antibody

Western Blot: SPOP Antibody [NBP1-33090] - Western blot analysis of SPOP on 293T lysates using NBP1-33090. Rabbit IgG Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SPOP (transcript variant 6)

SPOP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SPOP (1-347, His-tag)

SPOP Human Purified > 90 % E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

SPOP (1-347, His-tag)

SPOP Human Purified > 90 % E. coli
50 µg / €370.00
  Acris Antibodies GmbH

SPOP

SPOP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SPOP

SPOP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

SPOP

SPOP Human Purified
0.25 mg / €1,140.00
  Novus Biologicals Inc.

SPOP

SPOP Human Purified
50 µg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SPOP 293T Cell Transient Overexpression Lysate(Denatured)

SPOP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

SPOP overexpression lysate

SPOP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SPOP overexpression lysate

SPOP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SPOP overexpression lysate

SPOP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SPOP overexpression lysate

SPOP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SPOP overexpression lysate

SPOP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SPOP overexpression lysate

SPOP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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