SPRED3 antibody

Principal name

SPRED3 antibody

Alternative names for SPRED3 antibody

EVE-3, Sprouty-related, EVH1 domain-containing protein 3

Gene ID

399473 (SPRED3)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SPRED3 antibody

Spred3 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1 and Spred2, Spred3 contains and EVH1 domain in its amino terminus and a Sprouty-related cysteine-rich (SPR) domain in its C-terminus, but does not possess a functiol c-kit binding domain (KBD). The Spred proteins have also been implicated in the negative feedback regulation of FGF sigling in embryogenesis and angiogenesis. Although Spred3 was initially reported to be expressed in brain, at least one report also indicates that Spred3 can be found in liver. At least two isoforms of Spred3 are known to exist. This Spred3 antibody is predicted to have no cross-reactivity to Spred1 or Spred2.

General readings

King, J.A., et al. J. Hepatol. 44(4): 758-767 (2006)
Nonami, A., et al. J. Biol. Chem. 279(50): 52543-52551 (2004)
Mizoguchi, M., et al. Neurogenetics 5(1): 81-82 (2004)
Kato, R., et al. Biochem. Biophys. Res. Commun. 302(4): 767-772 (2003)

3 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SPRED3 (Center) antibody

Western blot analysis of Spred3 in human brain tissue lysate with Spred3 antibody at (A) 2 and (B) 4 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SPRED3 Control Peptide

SPRED3
50 µg / €160.00
  Acris Antibodies GmbH

SPRED3 (N-term) antibody

Immunohistochemistry analysis in human pancreas tissue (Formalin-fixed, Paraffin-embedded) using SPRED3 antibody Cat.-No. AP54031PU-N (N-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SPRED3 antibody for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

3 Item(s)

per page
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