SPTLC2 antibody

Principal name

SPTLC2 antibody

Alternative names for SPTLC2 antibody

Serine palmitoyltransferase 2, SPT 2, SPT2, LCB 2, LCB2, LCB2a, KIAA0526, Serine-palmitoyl-CoA transferase 2, Long chain base biosynthesis protein 2

SwissProt ID

O15270 (Human), P97363 (Mouse)

Gene ID

9517 (SPTLC2), 20773 (Sptlc2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of SPTLC2 antibody

SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c

General readings

Hornemann,T., (2007) Biochem. J. 405 (1), 157-164

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SPTLC2 (C-term) antibody

  Rabbit Polyclonal SPT2 Antibody  
Western blot analysis of SPT2 in 3T3 cell lysate with SPT2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SPTLC2 antibody

  Rabbit Polyclonal Anti-SPTLC2 Antibody  
WB Suggested Anti-SPTLC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

SPTLC2 (C-term) antibody

Western blot analysis of anti-SPTLC2 (C-term) Pab (Cat. #AP12257PU-N) to detect SPTLC2 in mouse liver tissue lysate. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Sptlc2 - mouse gene knockout kit via CRISPR

Sptlc2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Sptlc2 - mouse gene knockout kit via CRISPR

Sptlc2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sptlc2 - mouse gene knockout kit via CRISPR

Sptlc2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sptlc2 - mouse gene knockout kit via CRISPR

Sptlc2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SPTLC2 (mGFP-tagged) - Human serine palmitoyltransferase, long chain base subunit 2 (SPTLC2), 200 uL, >10^7 TU/mL

Lenti ORF particles, SPTLC2 (mGFP-tagged) - Human serine palmitoyltransferase, long chain base subunit 2 (SPTLC2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SPTLC2 (Myc-DDK tagged) - Human serine palmitoyltransferase, long chain base subunit 2 (SPTLC2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, SPTLC2 (Myc-DDK tagged) - Human serine palmitoyltransferase, long chain base subunit 2 (SPTLC2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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